ABT161
Anti-HepaCAM-1 Antibody
from rabbit, purified by affinity chromatography
别名:
Hepatocyte cell adhesion molecule, Protein hepaCAM
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
human
Application:
IHC, WB
Citations:
-
biological source
rabbit
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
species reactivity (predicted by homology)
horse (based on 100% sequence homology)
technique(s)
immunohistochemistry: suitable (paraffin), western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... HEPACAM(220296)
General description
Gene HepaCAM, which is frequently silenced in hepatocellular carcinoma (HCC), encodes an Ig-like transmembrane glycoprotein. This glycoprotein serves as a type of cell adhesion molecule (CAM), which interacts with other CAMs on the adjacent cell surface or with proteins found in the extracellular matrix. It is observed to regulate cellular growth and cell-matrix adhesion. It also plays a role in cellular migration.
~53 kDa observed. Two isoforms at ~40 kDa and ~46 kDa are known to exist. This protein is known to be glycosylated in HT-1080 and HEPG2 cell lysates (Chung, M. M., et al. (2005). J Hepatol. 42(6):833-841.).
Immunogen
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human HepaCAM-1.
Application
Detect the HepaCAM-1 protein using this Anti-HepaCAM-1 validated for use in WB & IHC.
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected HepaCAM-1 in human liver and human breast carcinoma tissues.
Biochem/physiol Actions
Other homologies: Mouse, Rat, and Bovine (96% sequence homology).
This antibody recognizes the cytoplasmic domain of HepaCAM-1.
Analysis Note
Evaluated by Western Blot in human liver tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected HepaCAM-1 in 10 µg of human liver tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected HepaCAM-1 in 10 µg of human liver tissue lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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