Anti-BCAR3 Antibody

Breast cancer anti-estrogen resistance protein 3 (BCAR3), also known as Novel SH2-containing protein 2 (NSP2) and SH2 domain-containing protein 3B (SH2D3B) is an adapter protein that regulates the proliferation in breast cancer cells. BCAR3 may also be regulated by cellular adhesion to extracellular matrix proteins. BCAR3 is found in several cancer cell lines; however, it is not found in nonmalignant breast tissue. When BCAR3 is overexpressed, it confers anti-estrogen resistance in breast cancer cell lines.

KLH-conjugated linear peptide corresponding to human BCAR3.

Anti-BCAR3 Antibody is a highly specific rabbit polyclonal antibody, that targets Breast cancer Anti-estrogen resistance protein 3 & has been tested in western blotting.

Research Category
Apoptosis & Cancer

Evaluated by Western Blotting in mouse kidney tissue lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected BCAR3 in 15 µg of mouse kidney tissue lysate.

~104 kDa observed

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
Mouse kidney tissue lysate

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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