biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human, rat
technique(s)
immunohistochemistry: suitable, western blot: suitable
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... KLHL1(57626)
General description
The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. KLHL1 contains one BTB (POZ) domain and six Klech repoeats. KLHL1 may play an important role in organizing the actin cytoskeleton of the brain cells. Mutations associated with KLHL1 are inplicated in spinocerebellar ataxia type 8 (SCA8).
~100 kDa observed
Immunogen
KLH-conjugated linear peptide corresponding to human KLHL1.
Application
Detect Kelch-like 1 using this rabbit polyclonal antibody, Anti-KLHL1 Antibody validated for use in western blotting & IHC.
Immunohistochemistry Analysis: 10 µg/mL from a representative lot detected KLHL1 in rat brain tissue.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Cytoskeleton
Cytoskeleton
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Human brain tissue lysate
Human brain tissue lysate
Evaluated by Western Blotting in human brain tissue lysate.
Western Blotting Analysis: 4 µg/mL of this antibody detected KLHL1 in 15 µg/mL of human brain tissue lysate.
Western Blotting Analysis: 4 µg/mL of this antibody detected KLHL1 in 15 µg/mL of human brain tissue lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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