产品名称
Dopamine D2 Receptor, control peptide for AB5084P,
biological source
human
form
liquid
manufacturer/tradename
Chemicon®
concentration
1 mg/mL
technique(s)
cell based assay: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Quality Level
General description
28 amino acid peptide sequence from the human D2 R within the cytoplasmic loop #3. The 28 amino acid sequence is shared by both the long and short form.
Application
For use in blocking the staining of AB5084P.
Optimal working dilution must be determined by the end user.
Optimal working dilution must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
Physical form
Liquid in PBS, pH 7.5. No preservative.
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
F J Monsma et al.
Nature, 342(6252), 926-929 (1989-12-21)
Dopamine receptor belong to a large class of neurotransmitter and hormone receptors that are linked to their signal transduction pathways through guanine nucleotide binding regulatory proteins (G proteins). Pharmacological, biochemical and physiological criteria have been used to define two subcategories
Hong Wang et al.
The Journal of comparative neurology, 442(4), 392-404 (2002-01-17)
Glutamatergic neurons within the deep layers of the prefrontal cortex and dopaminergic neurons of the substantia nigra pars compacta preferentially terminate in patch-like regions within the caudate putamen nucleus (CPN). Activation of dopamine D2 receptors is known to potently modulate
V A Boundy et al.
Molecular pharmacology, 43(5), 666-676 (1993-05-01)
Multiple subtypes of dopamine receptors with similar properties have been described. Ligands that have been shown to interact with a single subtype of receptor do not yet exist. The use of immunologic methods provides an alternative approach to distinguish receptors
Production and characterization of a monoclonal antibody to dopamine D2 receptor: comparison with a polyclonal antibody to a different epitope.
Farooqui, S M, et al.
Biochemical and biophysical research communications, 184, 661-667 (1992)
R Dal Toso et al.
The EMBO journal, 8(13), 4025-4034 (1989-12-20)
Cloned human dopamine D2 receptor cDNA was isolated from a pituitary cDNA library and found to encode an additional 29 amino acid residues in the predicted intracellular domain between transmembrane regions 5 and 6 relative to a previously described rat
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