AP500
Goat Anti-Mouse IgM µ chain Antibody, Species Adsorbed
1 mg/mL, Chemicon®
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.46
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA
Citations:
2
biological source
goat
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
secondary antibodies
clone
polyclonal
species reactivity
mouse
manufacturer/tradename
Chemicon®
concentration
1 mg/mL
technique(s)
ELISA: suitable
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
General description
IgM constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and predominates in certain antibody responses such as ′natural′ blood group antibodies. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. The gene for the mu constant region contains four domains separated by short intervening sequences.
Application
This Goat anti-Mouse IgM µ chain Antibody, Species Adsorbed is validated for use in ELISA for the detection of Mouse IgM µ chain.
Biochem/physiol Actions
Reacts with heavy chain of mouse IgM. Absorbed for mouse IgG1, IgG2a, IgG2b, IgG3 and IgA, pooled human sera and purified human paraproteins. Minimal cross reactivity with human immunoglobulins. Reactivity with other species has not been determined.
Physical form
Purified by affinity chromatography on mouse IgM covalently linked to agarose. Liquid in 1.0 mL of 100 mM borate buffered saline, pH 8.2.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Pharmacologically Inferred Glycolysis and Glutaminolysis Requirement of B Cells in Lupus-Prone Mice.
Seung-Chul Choi et al.
Journal of immunology (Baltimore, Md. : 1950), 208(9), 2098-2108 (2022-04-08)
Several studies have shown an enhanced metabolism in the CD4+ T cells of lupus patients and lupus-prone mice. Little is known about the metabolism of B cells in lupus. In this study, we compared the metabolism of B cells between
Christoph Schultheiß et al.
Science advances, 10(34), eadl3975-eadl3975 (2024-08-21)
Genetic TNFAIP3 (A20) inactivation is a classical somatic lymphoma lesion and the genomic trait in haploinsufficiency of A20 (HA20). In a cohort of 34 patients with HA20, we show that heterozygous TNFAIP3 loss skews immune repertoires toward lymphocytes with classical
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