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Merck
CN

AP500

Goat Anti-Mouse IgM µ chain Antibody, Species Adsorbed

1 mg/mL, Chemicon®

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.46
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA
Citations:
2
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biological source

goat

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

secondary antibodies

clone

polyclonal

species reactivity

mouse

manufacturer/tradename

Chemicon®

concentration

1 mg/mL

technique(s)

ELISA: suitable

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

General description

IgM constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and predominates in certain antibody responses such as ′natural′ blood group antibodies. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. The gene for the mu constant region contains four domains separated by short intervening sequences.

Application

This Goat anti-Mouse IgM µ chain Antibody, Species Adsorbed is validated for use in ELISA for the detection of Mouse IgM µ chain.

Biochem/physiol Actions

Reacts with heavy chain of mouse IgM. Absorbed for mouse IgG1, IgG2a, IgG2b, IgG3 and IgA, pooled human sera and purified human paraproteins. Minimal cross reactivity with human immunoglobulins. Reactivity with other species has not been determined.

Physical form

Purified by affinity chromatography on mouse IgM covalently linked to agarose. Liquid in 1.0 mL of 100 mM borate buffered saline, pH 8.2.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Christoph Schultheiß et al.
Science advances, 10(34), eadl3975-eadl3975 (2024-08-21)
Genetic TNFAIP3 (A20) inactivation is a classical somatic lymphoma lesion and the genomic trait in haploinsufficiency of A20 (HA20). In a cohort of 34 patients with HA20, we show that heterozygous TNFAIP3 loss skews immune repertoires toward lymphocytes with classical
Seung-Chul Choi et al.
Journal of immunology (Baltimore, Md. : 1950), 208(9), 2098-2108 (2022-04-08)
Several studies have shown an enhanced metabolism in the CD4+ T cells of lupus patients and lupus-prone mice. Little is known about the metabolism of B cells in lupus. In this study, we compared the metabolism of B cells between

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