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Merck
CN

AP506

Goat Anti-Human Ig λ chain Antibody

1 mg/mL, Chemicon®

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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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产品名称

Goat Anti-Human Ig λ chain Antibody, 1 mg/mL, Chemicon®

biological source

goat

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

secondary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

concentration

1 mg/mL

technique(s)

ELISA: suitable

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Application

Detect Human Ig λ chain using this Goat anti-Human Ig λ chain Antibody validated for use in ELISA.
Research Category
Secondary & Control Antibodies
Research Sub Category
Fragment Specific Secondary Antibodies

Biochem/physiol Actions

Reacts with human lambda light chains. Absorbed for human myeloma proteins with kappa light chains.
The antibody reacts with human lambda light chains as demonstrated by ELISA and flow cytometry.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Antibody molecules typically comprise two immunoglobulin light chains covalently bound to a pair of heavy chains. Immunoglobulin light chains occur in two types, designated by the Greek letters kappa and lambda. Kappa and lambda light chains are approximately 250 amino acids in length with an average mass of about 25 kDa. The ratio of kappa to lambda found in the immunoglobulin population varies by species.

Immunogen

Epitope: Ig lambda chain
Prepared from pooled antisera from goats hyperimmunized with human myeloma proteins with kappa light chains.

Physical form

Affinity Chromatography
Purified by affinity chromatography on pooled human Igs with lambda light chains covalently linked to agarose. Liquid in 1.0 mL of 100 mM borate buffered saline, pH 8.2.

Preparation Note

Maintain refrigerated at 2°-8°C under sterile conditions for up to twelve months from date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Repr. 1B

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Kathrin Andrich et al.
The Journal of biological chemistry, 292(6), 2328-2344 (2016-12-30)
Intervention into amyloid deposition with anti-amyloid agents like the polyphenol epigallocatechin-3-gallate (EGCG) is emerging as an experimental secondary treatment strategy in systemic light chain amyloidosis (AL). In both AL and multiple myeloma (MM), soluble immunoglobulin light chains (LC) are produced

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