biological source
rabbit
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
form
liquid
contains
≤0.1% sodium azide as preservative
species reactivity
mouse, rat, human
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
dilution
(Immunoblotting (3-10 µg/mL))
isotype
IgG
shipped in
ambient
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... UBE2Q1(55585)
General description
Anti-GTAP, rabbit polyclonal, recognizes the ~67 kDa GTAP protein in HEK293 cells. It is validated for use in Western blotting.
Protein A purified rabbit polyclonal antibody. Recognizes the ~67 kDa GTAP protein.
Recognizes the ~67 kDa GTAP protein in HEK293 cells.Hu Entrez ID: 55585 Mu Entrez ID: 70093 Rat Entrez ID: 295292 Target NCBI Accession: HP 060052.3 Target SwissProt: Q7Z7E8
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). GTAP is a member of the E2 ubiquitin-conjugating enzyme family. GTAP may participate in intercellular adhesion and embryonic development. GTAP is thought to play a role in stem cell development via its regulation of laminin-dependent embryonic cell adhesion and the formation of embryoid bodies.
Immunogen
A synthetic peptide corresponding to amino acids 7-22 (QGQQQPGPGQQLGGQG) of human GTAP, conjugated to KLH.
Human
Application
Immunoblotting (3-10 g/ml)
Physical form
In PBS.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Other Notes
Due to a high degree of sequence identity, this antibody is also expected to react with mouse and rat GTAP. Antibody should be titrated for optimal results in individual systems.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Regulatory Review (Z)
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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