CBL458
Anti-CD49f Antibody, clone 4F10
clone 4F10, Chemicon®, from mouse
别名:
Integrin alpha6
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
4F10, monoclonal
Application:
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
immunohistochemistry
immunoprecipitation (IP)
Species reactivity:
human
Citations:
7
Technique(s):
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
Uniprot accession no.:
产品名称
Anti-CD49f Antibody, clone 4F10, clone 4F10, Chemicon®, from mouse
antibody form
affinity isolated antibody
biological source
mouse
conjugate
unconjugated
antibody product type
primary antibodies
clone
4F10, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
isotype
IgG2b
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ITGA6(3655)
Application
This Anti-CD49f Antibody, clone 4F10 is validated for use in FC, IP, IH for the detection of CD49f.
Immunohistological studies on frozen sections
Immunoprecipitation of the laminin receptor
Flow Cytometry
Optimal working dilutions must be determined by the end user.
Immunoprecipitation of the laminin receptor
Flow Cytometry
Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
Biochem/physiol Actions
This antibody is specific to the integrin alpha6 chain which is expressed on epithelial and endothelial basement membrane. The VLA alpha6 chain, which consists of a single disulphide linked 120 kDa subunit and a small doublet subunit of 25/30 kDa, is non covalently associated with the VLA beta-chain (CD29) in VLA-6 or alpha6/beta1 complex or with integrin beta4 chain (alpha6/beta4).
The antigen is also expressed on platelets, monocytes, thymocytes and T lymphocytes.
FUSION PARTNER: NS1 myeloma cell line
The antigen is also expressed on platelets, monocytes, thymocytes and T lymphocytes.
FUSION PARTNER: NS1 myeloma cell line
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
Cell line SW/222 (Human colorectal carcinoma)
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: MAB2254
Physical form
Format: Purified
The monoclonal was purified by protein A affinity chromatography and is presented as a liquid in phosphate buffered saline containing 10mM sodium azide and 1 mg/mL bovine serum albumin.
Preparation Note
Store an 2-8°C for up to 12 months from date of receipt. For long term storage aliquot antibody into small volumes and store at -20°C. Avoid repeated freeze-thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Adam Wahlsten et al.
Biomaterials, 273, 120779-120779 (2021-05-02)
The clinical treatment of large, full-thickness skin injuries with tissue-engineered autologous dermo-epidermal skin substitutes is an emerging alternative to split-thickness skin grafting. However, their production requires about one month of in vitro cell and tissue culture, which is a significant
Bryan W Day et al.
Cancer cell, 23(2), 238-248 (2013-02-16)
Significant endeavor has been applied to identify functional therapeutic targets in glioblastoma (GBM) to halt the growth of this aggressive cancer. We show that the receptor tyrosine kinase EphA3 is frequently overexpressed in GBM and, in particular, in the most
Laminin-5 induces osteogenic gene expression in human mesenchymal stem cells through an ERK-dependent pathway.
Klees, RF; Salasznyk, RM; Kingsley, K; Williams, WA; Boskey, A; Plopper, GE
Molecular Biology of the Cell null
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