产品名称
抗-PECAM-1抗体，人PECAM-1结构域3-6，克隆HC1/6, clone HC1/6, Chemicon®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
clone
HC1/6, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunoprecipitation (IP): suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PECAM1(5175)
相关类别
Analysis Note
对照
活化的小胶质细胞
活化的小胶质细胞
Application
CD31在白细胞向炎症部位迁移和血管生成过程中的作用研究
该抗体会在冷冻组织切片上染色
适用于免疫沉淀研究
适用于标记FITC或R-PE时的间接或直接流式细胞术
适用于蛋白酶预处理后的福尔马林固定石蜡包埋切片。
最佳工作稀释度必须由最终用户进行确定。
该抗体会在冷冻组织切片上染色
适用于免疫沉淀研究
适用于标记FITC或R-PE时的间接或直接流式细胞术
适用于蛋白酶预处理后的福尔马林固定石蜡包埋切片。
最佳工作稀释度必须由最终用户进行确定。
抗-PECAM-1抗体，人PECAM-1结构域3-6，克隆HC1/6是抗PECAM-1抗体，适用于FC、IH、IH(P) & IP。
Biochem/physiol Actions
与一个130-140 kDa的跨膜糖蛋白反应，该糖蛋白在血管间室的细胞中广泛表达。 CD31在扁桃体、肺和肾脏的血小板、培养内皮细胞、单核细胞、正常组织巨噬细胞以及结节病和麻风病等疾病的皮肤活检组织中表达。
FUSION PARTNER：P3-x63Ag8.653骨髓瘤细胞系
FUSION PARTNER：P3-x63Ag8.653骨髓瘤细胞系
Immunogen
表位：人PECAM-1的结构域3-6
Other Notes
浓度：请参考批次特异性浓缩物的检验报告。
Physical form
形式：纯化
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Gina Lisignoli et al.
Journal of cellular physiology, 220(2), 401-409 (2009-04-15)
Bone marrow stromal cells (MSCs) and osteoblasts are the two main non-haematopoietic cellular components of human bone tissue. To identify novel osteoblast-related molecules, we performed a gene expression profiling analysis comparing MSCs and osteoblasts isolated from the same donors. Genes
Yu-Ting Huang et al.
Cellular signalling, 20(8), 1521-1527 (2008-05-27)
Sphingosine 1-phosphate (S1P) is a multifunctional phospholipid which acts through a specific family of G protein-coupled receptors. Platelet/endothelial cell adhesion molecule-1 (PECAM-1) form trans-homophilic binding at lateral cell border. Upon stimulation, its cytoplasmic tyrosine residues could be phosphorylated and interact
Fumiko Obata et al.
Toxins, 14(2) (2022-02-25)
Shiga toxin-producing Escherichia coli (STEC) causes proximal tubular defects in the kidney. However, factors altered by Shiga toxin (Stx) within the proximal tubules are yet to be shown. We determined Stx receptor Gb3 in murine and human kidneys and confirmed
Guiting Lin et al.
Stem cells and development, 17(6), 1053-1063 (2008-07-04)
Adipose tissue-derived stem cells (ADSC) are routinely isolated from the stromal vascular fraction (SVF) of homogenized adipose tissue. Freshly isolated ADSC display surface markers that differ from those of cultured ADSC, but both cell preparations are capable of multipotential differentiation.
T M Herndon et al.
Journal of immunology (Baltimore, Md. : 1950), 166(9), 5654-5664 (2001-04-21)
The transcription factor NF-kappaB is a critical regulator of T cell function that becomes strongly activated in response to coengagement of TCR and CD28. Although events immediately proximal to NF-kappaB activation are well understood, uncertainty remains over which upstream signaling
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