Anti-Insulin-like Growth Factor-I Antibody, clone M23

Immunohistological staining of tissue sections on frozen or formalin fixed paraffin wax embedded sections

Optimal working dilutions must be determined by the end user.

Research Category
Signaling

Research Sub Category
Insulin/Energy Signaling

This Anti-Insulin-like Growth Factor-I Antibody, clone M23 is validated for use in IH(P) for the detection of Insulin-like Growth Factor-I.

The basic IGF-1-like forms (pl>9.0) showed substantial cross-reactivity, as did rat and mouse sera. Monoclonal antibody BM23 was capable of abolishing the biological activities of IGF-1 in vitro bioassays for insulin-like, mitogenic and sulphation activities.

AFFINITY CONSTANT: The affinity of monoclonal antibody BM23 for IGF-1 was 1 x 10E10 L/mole and the cross reactivities of IGF-2, MSA and porcine insulin were 1%, 0.05% and 0.0001% respectively

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Purified human IGF-1.

Format: Purified

The monoclonal is presented at a concentration of 100μg/1ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.

For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany