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Merck
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CBL555

Anti-CD34 Class III Antibody, clone 581

clone 581, Chemicon®, from mouse

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
581, monoclonal
Application:
flow cytometry
Species reactivity:
human
Citations:
5
Technique(s):
flow cytometry: suitable
Uniprot accession no.:
P28906

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产品名称

Anti-CD34 Class III Antibody, clone 581, clone 581, Chemicon®, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

581, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable

isotype

IgG1

NCBI accession no.

NM_001025109.1
NM_001773.2

UniProt accession no.

P28906

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... CD34(947)

相关类别

Application

Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Study of the Class III CD34 epitope by FACS

Optimal working dilutions must be determined by the end user.
This Anti-CD34 Antibody, Class III, clone 581 is validated for use in FC for the detection of CD34 Class III.

Biochem/physiol Actions

Clone 581 reacts with the class III CD34 epitope is resistant to neuraminidase, chymopapain and glycoprotease.

The antibody reacts with a single-chain 105-120 kDa heavily O-glycosylated transmembrane glycoprotein which is expressed on haematopoietic progenitor cells, vascular endothelium and some tissue fibroblasts. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C suggesting a putative role in signal transduction. CD34 may also play a role in the adhesion of specific antigens to endothelium.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Physical form

Format: Purified
Protein G affinity chromatography. The monoclonal is presented at a concentration of 100μg/1ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.

Preparation Note

For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Teresa Massam-Wu et al.
Methods in molecular biology (Clifton, N.J.), 1722, 249-260 (2017-12-22)
We present a method to capture mesenchymal stromal cells (MSCs) by adhesion to extracellular matrix (ECM) molecules under flow conditions. The technique simulates a physiological system and exploits the natural biological interactions of cells, through integrin receptors, with their ECM.
Alkistis Kapelouzou et al.
Journal of vascular research, 54(3), 156-169 (2017-05-10)
Atherosclerosis is the major cause of cardiovascular disease; hypercholesterolemia is a major risk factor. We hypothesized that specific TLR members (TLR2, TLR3, TLR4, TLR8) may play a role in atherosclerosis progression and its accompanying inflammatory response. We determined the association
Mahmoud Yousefifard et al.
Journal of stem cells & regenerative medicine, 18(2), 53-63 (2023-01-31)
Few studies are conducted on the efficacy of human adipose-derived stem cells (ADSCs) in spinal cord injury (SCI) management and electrophysiological changes in the spinal cord. Therefore, the present study aimed to determine the effect of ADSCs on neuropathic pain

相关内容

Antibodies to Cancer Biomarkers
Anti-CD34 Class III, clone 581 - Data Sheet

MOUSE ANTI-HUMAN CD34 TYPE III MONOCLONAL ANTIBODY

Human Stem Cell Systems

As the focus of stem cell research undergoes a transition from animal to human models, researchers are in critical need of validated products to support the isolation, maintenance, differentiation, and characterization of human stem cells. While many reagents designed for rodent systems can be applied to human stem cell studies, they are not truly optimized for robust human stem cell culture or analysis. This is why human stem cell researchers have always trusted EMD Millipore, the first provider of commercially available human embryonic stem cells and human neural stem cell lines, to accelerate their research. All of our human stem cell systems are extensively tested in defined media culture, and differentiated progeny are comprehensively characterized with highly validated antibodies and detection reagents.

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