产品名称
Anti-Adrenocorticotropic Hormone Antibody, CT, clone 56, clone 56, Chemicon®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
56, monoclonal
species reactivity
rat, human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunohistochemistry: suitable (paraffin)
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MC2R(4158)
rat ... Mc2R(282839)
Application
Anti-Adrenocorticotropic Hormone Antibody, C-terminus, clone 56 is an antibody against Adrenocorticotropic Hormone for use in ELISA, IH(P).
Research Category
Neuroscience
Neuroscience
Research Sub Category
CNS Control of Metabolism
Hormones & Receptors
CNS Control of Metabolism
Hormones & Receptors
This antibody reacts with solid phase ACTH either captured as part of a sandwich or adsorbed as a solid phase antigen and as such is suitable for serum assay development
The antibody is also reactive on formalin fixed paraffin wax embedded tissue and is therefore suitable for immunocytochemistry
Optimal working dilutions must be determined by the end user.
The antibody is also reactive on formalin fixed paraffin wax embedded tissue and is therefore suitable for immunocytochemistry
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
This antibody is specific for CLIP (17-39 ACTH) and no cross reaction with Synacthen (1-24 ACTH).
KNOWN SPECIES CROSS REACTIVITY: Positive with rat C-terminal ACTH
KNOWN SPECIES CROSS REACTIVITY: Positive with rat C-terminal ACTH
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
ACTH-BSA Conjugate
Epitope: C-terminus
Physical form
Format: Purified
The monoclonal is presented as 1mg in 1ml phosphate buffered saline containing 0.1% sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application.
Preparation Note
For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Andrea Polito et al.
PloS one, 6(11), e25905-e25905 (2011-11-11)
The mechanisms of septic shock-associated adrenal insufficiency remain unclear. This study aimed at investigating the synthesis of corticotropin-releasing hormone (CRH) and vasopressin (AVP) by parvocellular neurons and the antehypophyseal expression of ACTH in human septic shock and in an experimental
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