产品名称
Anti-CD126 Antibody, clone B-R6, clone B-R6, Chemicon®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
B-R6, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... IL6R(3570)
Application
Flow cytometry: 1:50. Use 10 μL of this dilution to label 10e6 cells in 100 μL.
Immunohistochemistry on frozen sections.
Immunoprecipitation.
ELISA
Optimal working dilutions must be determined by the end user.
Immunohistochemistry on frozen sections.
Immunoprecipitation.
ELISA
Optimal working dilutions must be determined by the end user.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Immunoglobulins & Immunology
This Anti-CD126 Antibody, clone B-R6 is validated for use in ELISA, FC, IP, IH for the detection of CD126.
Biochem/physiol Actions
This antibody recognizes both the soluble and membrane bound human IL-6 receptor. The antibody will inhibit IL-6 mediated proliferation of XG-1 cells and partially blocks the binding of IL-6 to its receptor.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
CHO cells transfected with a cDNA of the human IL-6 receptor.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Format: Purified
The monoclonal was purified by ion exchange chromatography and is presented as a liquid in phosphate buffered saline, pH 7.4, containing 0.09% sodium azide.
Preparation Note
Maintain at 2°-8°C for up to 12 months from date of receipt in undiluted aliquots.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Jakob Vejby Larsen et al.
Molecular and cellular biology, 37(11) (2017-03-08)
Interleukin-6 (IL-6) is a multifunctional cytokine with important functions in various physiologic processes. Mice lacking IL-6 exhibit multiple phenotypic abnormalities, such as an inadequate immune and acute-phase response, and elevated levels of circulating IL-6 have been found to accompany several
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