Merck
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CBL714

Sigma-Aldrich

Anti-CD126 Antibody, clone B-R6

clone B-R6, Chemicon®, from mouse

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别名:
IL-6 Receptor, alpha Chain
eCl@ss:
32160702

生物来源

mouse

质量水平

抗体形式

purified antibody

antibody product type

primary antibodies

克隆

B-R6, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable

同位素/亚型

IgG1

UniProt登记号

运输

wet ice

target post-translational modification

unmodified

Gene Information

human ... IL6R(3570)

特异性

This antibody recognizes both the soluble and membrane bound human IL-6 receptor. The antibody will inhibit IL-6 mediated proliferation of XG-1 cells and partially blocks the binding of IL-6 to its receptor.

免疫原

CHO cells transfected with a cDNA of the human IL-6 receptor.

应用

Flow cytometry: 1:50. Use 10 μL of this dilution to label 10e6 cells in 100 μL.

Immunohistochemistry on frozen sections.

Immunoprecipitation.

ELISA

Optimal working dilutions must be determined by the end user.
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
This Anti-CD126 Antibody, clone B-R6 is validated for use in ELISA, FC, IP, IH for the detection of CD126.

外形

Format: Purified
The monoclonal was purified by ion exchange chromatography and is presented as a liquid in phosphate buffered saline, pH 7.4, containing 0.09% sodium azide.

储存及稳定性

Maintain at 2°-8°C for up to 12 months from date of receipt in undiluted aliquots.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Jakob Vejby Larsen et al.
Molecular and cellular biology, 37(11) (2017-03-08)
Interleukin-6 (IL-6) is a multifunctional cytokine with important functions in various physiologic processes. Mice lacking IL-6 exhibit multiple phenotypic abnormalities, such as an inadequate immune and acute-phase response, and elevated levels of circulating IL-6 have been found to accompany several

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