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CC43

抗-Cdh1（Ab-2）小鼠mAb（DH01）

Name: 抗-Cdh1（Ab-2）小鼠mAb（DH01）
Brand: MM

liquid, clone DH01, Calbiochem^®

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关于此项目

NACRES:

NA.43

UNSPSC Code:

12352203

Clone:

DH01, monoclonal

Species reactivity:

human

Application:

—

Citations:

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属性

biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

DH01, monoclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human

manufacturer/tradename

Calbiochem^®

storage condition

do not freeze

dilution

(Immunoblotting (1 µg/mL)
Immunoprecipitation (2 µg/mg protein lysate))

isotype

IgG1

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... CDH1(999)

说明

General description

抗CDH1（Ab-2），小鼠单克隆，克隆DH01，可识别大鼠1细胞中约55 kDa Cdh-1蛋白。它已被验证可用于蛋白质印迹和免疫沉淀。

用指定的免疫原免疫BALB/c小鼠，并将脾细胞与Sp2/0小鼠骨髓瘤融合而产生的纯化的小鼠单克隆抗体。识别约为55 kDa的ID1蛋白。

识别大鼠1细胞中~55 kDa Cdh-1蛋白。

Immunogen

人

重组人Cdh1蛋白

Application

免疫印迹（1 g/mL）
免疫沉淀（2 g/mg蛋白裂解物）

Packaging

请参考特定浓度批号的标签。

Physical form

在10 mM PBS，0.2%BSA，pH值7.4中。

Analysis Note

阳性对照
：KAT或LS174T细胞

阴性对照
正常小鼠血清

Other Notes

Kramer, E.R., et al. 2000 Mol.Biol. Cell11, 1555.
Petersen, B.O., et al. 2000 Genes Dev.14, 2330.
Pfleger, C.M., et al. 2001 Genes Dev.15, 1759.
Sorensen, C.S., et al. 2001 Mol.Cell Biol.21, 3692.
Gieffers, C., et al. 1999 Proc.Natl.Acad.Sci. USA96, 11317.
Visintin, R., et al. 1997 Science278, 460.

不与其他含有WD重复序列的蛋白质（包括Cdc20）发生交叉反应。在单个系统中，应对抗体进行滴定以获得最佳结果。

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

毒性：标准处理（A）

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存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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The human T-lymphotropic virus type 1 (HTLV-1) Tax binds the anaphase promoting complex (APC) and activates it ahead of schedule. Here, we show that APC activation by Tax induces rapid senescence (tax-IRS) independently of p53 and pRB. In response to

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We previously reported that aberrant TGF-β/Smad2/3 signaling in endometrial cancer (ECA) leads to continuous ubiquitylation of p27(kip1)(p27) by the E3 ligase SCF-Skp2/Cks1 causing its degradation, as a putative mechanism involved in the pathogenesis of this cancer. In contrast, normal intact

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APC/CCdh1 is a ubiquitin ligase with roles in numerous diverse processes, including control of cellular proliferation and multiple aspects of the DNA damage response. Precise regulation of APC/CCdh1 activity is central to efficient cell-cycle progression and cellular homeostasis. Here, we

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货号	GTIN
CC43-100UG	04055977228472