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CCYTOMAG-90K

MILLIPLEX® 犬细胞因子/趋化因子磁珠板 - 免疫学多重分析

Configurable Canine Cytokine/Chemokine 13-Plex Panel

别名:

canine interleukin immunoassay panel, luminex canine cytokine chemokine growth factor multiplex assay, luminex canine pro inflammatory anti inflammatory cytokine panel, millipore canine inflammation multiplex kit

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关于此项目

UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000

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产品名称

MILLIPLEX® 犬细胞因子/趋化因子磁珠板 - 免疫学多重分析, Configurable Canine Cytokine/Chemokine 13-Plex Panel

species reactivity

canine

manufacturer/tradename

Milliplex®

Quality Level

200

packaging

1 ea of

assay range

accuracy: 91-109%
sensitivity: 13.6 pg/mL
(IFN-γ)
sensitivity: 21.0 pg/mL
(MCP-1)
sensitivity: 21.7 pg/mL
(IL-8)
sensitivity: 3.2 pg/mL
(IP-10)
sensitivity: 3.5 pg/mL
(IL-2)
sensitivity: 3.7 pg/mL
(IL-6)
sensitivity: 5.3 pg/mL
(KC-like)
sensitivity: 5.8 pg/mL
(IL-18)
sensitivity: 6.1 pg/mL
(TNFα)
sensitivity: 7.5 pg/mL
(IL-7)
sensitivity: 8.5 pg/mL
(IL-10)
sensitivity: 9.0 pg/mL
(IL-15)
sensitivity: 9.2 pg/mL
(GM-CSF)
standard curve range: 12.2-50,000 pg/mL
(All analytes)

technique(s)

multiplexing: suitable

input

serum plasma (Cell culture, cell culture supernatants)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

相关类别

Biochem/physiol Actions

交叉反应性
抗体与该面板中任何其他分析物之间的交叉反应性都为无法检测或可忽略。
检测板内不同分析物之间不存在或可忽略的交叉反应性。

Features and Benefits

通过在此面板中选择可用的分析物来设计多重试剂盒。

Preparation Note

试剂盒组分建议的存储温度为2-8°C。

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

General description

In addition to studying inflammation for dog nutrition and disease research, canine animal models are important for human biomedical research and drug development. Cytokine and chemokines are molecular mediators of immune cell response in inflammation and immunity. Quantification of cytokines and chemokines is essential to understanding the immune system, as well as for researching disease states such as autoimmune, allergic reactions, sepsis, and cancer.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 13 analytes in canine serum, plasma, and cell culture supernatants.

Analytes included: GM-CSF, IFNγ, IP-10, IL-2, IL-6, IL-7, IL-8, IL-10, IL-15, IL-18, KC-like, MCP-1, TNF-α

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

存储类别

10 - Combustible liquids

wgk

WGK 3

法规信息

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Anna Brunner et al.
Frontiers in veterinary science, 8, 652479-652479 (2021-07-06)
Background: The degree of systemic inflammation, reperfusion injury and endothelial activation are potentially important determinants of clinical outcomes in dogs with gastric dilatation volvulus (GDV). Objective: To evaluate plasma concentrations and kinetics of inflammatory markers in dogs with GDV over
Herman Borghys et al.
Journal of Alzheimer's disease : JAD, 56(2), 763-774 (2016-12-31)
Understanding differences in Alzheimer's disease biomarkers before the pathology becomes evident can contribute to an improved understanding of disease pathogenesis and treatment. A decrease in amyloid-β (Aβ)42 in cerebrospinal fluid (CSF) is suggested to be a biomarker for Aβ deposition
Robert Goggs et al.
Veterinary record open, 7(1), e000366-e000366 (2020-08-22)
Platelet transfusion is indicated for haemorrhage due to severe thrombocytopenia and for trauma associated coagulopathy. Febrile non-haemolytic transfusion reactions are a common complication of platelet transfusions in people and may be due to accumulated inflammatory cytokines. The present study aimed
Carolini Kaid et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 28(5), 1276-1286 (2020-03-30)
Malignant brain tumors are among the most aggressive cancers with poor prognosis and no effective treatment. Recently, we reported the oncolytic potential of Zika virus infecting and destroying the human central nervous system (CNS) tumors in vitro and in immunodeficient mice
Pia Martiny et al.
Frontiers in veterinary science, 6, 208-208 (2019-07-19)
Septic peritonitis (SP) is common in dogs and is associated with high mortality. Early recognition is essential to maximizing survival and may be aided by biomarker measurement. The present study aimed to evaluate the ability of biomarkers to discriminate septic
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