DR1001
Anti-8-Hydroxyguanosine Goat pAb
liquid, Calbiochem®
别名:
Anti-8-OHG, Anti-8-oxo-G
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关于此项目
NACRES:
NA.43
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
-
Application:
—
Citations:
2
biological source
goat
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
form
liquid
does not contain
preservative
species reactivity (predicted by homology)
all
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
dilution
(ELISA (1:250,000)
Paraffin Sections (1:200, proteinase K pre-treatment recommended; see figure legend, )
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
General description
Goat polyclonal antibody supplied as undiluted serum. Recognizes 8-hydroxydeoxy-guanosine.
Recognizes 8-Hydroxydeoxyguanosine in Alzheimer′s disease brain tissue.
This Anti-8-Hydroxyguanosine Goat polyclonal antibody detects 8-Hydroxydeoxyguanosine in Alzheimer′s disease brain tissue. It is validated for use in ELISA and with paraffin sections.
Immunogen
8-Hydroxyguanosine
Application
ELISA (≥1:250,000)
Paraffin Sections (≥1:200, proteinase K pre-treatment recommended; see figure legend, see application references)
Physical form
Undiluted serum.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Analysis Note
Positive Control
Alzheimer’s disease brain tissue
Alzheimer’s disease brain tissue
Other Notes
Abe, T., et al. 2003. Neurosci. Lett.336, 105.
Parker, A.R., et al. 2002. Cancer Res.62, 7230.
Parker, A.R., et al. 2002. Cancer Res.62, 7230.
Does not cross-react with other naturally occurring nucleotides. Antibody should be titrated for optimal results in individual systems.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
N Gueven et al.
Cell death and differentiation, 14(6), 1149-1161 (2007-03-10)
Several different autosomal recessive genetic disorders characterized by ataxia with oculomotor apraxia (AOA) have been identified with the unifying feature of defective DNA damage recognition and/or repair. We describe here the characterization of a novel form of AOA showing increased
Joseph J Boyle et al.
The American journal of pathology, 174(3), 1097-1108 (2009-02-24)
Intraplaque hemorrhage accelerates atherosclerosis via oxidant stress and contributes to lesion development and destabilization. Normally, macrophages scavenge hemoglobin-haptoglobin (HbHp) complexes via CD163, and this process provokes the secretion of the anti-inflammatory atheroprotective cytokine interleukin (IL)-10. We therefore tested the hypothesis
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