EZHS42
Human Amyloid β42 ELISA Kit
measures and quantifies Amyloid β42 levels in 50 μL CSF, cell culture supernatent or plasma
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关于此项目
UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.84
Gene information:
human ... APP(351)
Input:
sample type plasma (K2 EDTA)
sample type serum
sample type cerebrospinal fluid (CSF)
sample type serum
sample type cerebrospinal fluid (CSF)
Assay range:
sensitivity: 8.0 pg/mL
(50 μl sample size), standard curve range: 16-500 pg/mL
(50 μl sample size), standard curve range: 16-500 pg/mL
Species reactivity:
human
Storage temp.:
2-8°C
Shipped in:
wet ice
产品名称
High Sensitivity Human Amyloid β42 ELISA,
Quality Level
description
This High Sensitivity Human Amyloid β42 ELISA is used to measure & quantify Amyloid β42 levels in Neuroscience research.
species reactivity
human
packaging
kit of 1 × 96 wells
parameter
50 μL sample volume (Overnight assay)
assay range
sensitivity: 8.0 pg/mL
(50 μl sample size), standard curve range: 16-500 pg/mL
technique(s)
ELISA: suitable
input
sample type plasma (K2 EDTA)
sample type serum
sample type cerebrospinal fluid (CSF)
application(s)
research use
detection method
colorimetric (450nm/590nm)
shipped in
wet ice
storage temp.
2-8°C
Gene Information
human ... APP(351)
General description
Amyloid beta peptides have been implicated in the etiology of Alzheimer’s disease. Amyloid beta 40 is the most prominent peptide and Amyloid beta 42 is the neurotoxic form. The Amyloid beta 42/40-ratio (AB ratio) has been reported as a better indicator of the Alzheimer pathology. Millipore’s High Sensitivity Human Amyloid β42 ELISA kit is used for the measurement of Amyloid β42 in cerebrospinal fluid, cell culture supernatants, primary neurons and plasma in a 96-well format.
Application
Research Category
Neuroscience
Neuroscience
Research Sub Category
Alzheimer′s Disease
Alzheimer′s Disease
This High Sensitivity Human Amyloid β42 ELISA is used to measure & quantify Amyloid β42 levels in Neuroscience research.
This assay requires 50 µl of sample and is an overnight assay.
Used to detect/quantify: Amyloid β42
Biochem/physiol Actions
The Amyloid β42 ELISA (HS) uses monoclonal anti-Aβ antibodies with high selectivity for human Aβ. The capture antibody recognizes the C-terminal end of Amyloid β1-42, which causes a high selectivity for Aβ42. The cross-reactivity of the used antibodies to other Amyloid peptides was tested by ELISA and BIACORE and shows no significant cross-reactivity to Aβ1-38, Aβ1-39, Aβ1-40, Aβ1-43 and Aβ1-44.
Preparation Note
Components in the kit can be stored up to 2 weeks at 2-8°C
Other Notes
Please contact Technical Service for linearity of dilution.
Disclaimer
For research use only. Not for use in diagnostic procedures.
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 3 - Met. Corr. 1 - Skin Sens. 1
wgk
WGK 3
存储类别
10 - Combustible liquids
法规信息
新产品
此项目有
Teresa Niccoli et al.
Current biology : CB, 26(17), 2291-2300 (2016-08-16)
Glucose hypometabolism is a prominent feature of the brains of patients with Alzheimer's disease (AD). Disease progression is associated with a reduction in glucose transporters in both neurons and endothelial cells of the blood-brain barrier. However, whether increasing glucose transport
Gunjan Manocha et al.
Current Alzheimer research, 15(12), 1123-1135 (2018-08-03)
Alzheimer's disease (AD) is associated with age-associated central nervous system degeneration and dementia. This decline in the function correlates with deposition of Aβ peptide containing plaques and associated reactive gliosis. The inflammatory phenotype of microglia, in particular, is often considered
Sooah Jang et al.
Psychiatry investigation, 15(2), 205-213 (2018-02-25)
Conventional methods for organotypic hippocampal tissue slice culture (OHSC) have shown several disadvantages or limitations regarding age of animals used, duration of culture and difficulty using neurodegenerative models. Therefore, we tried to establish OHSC from old 3xTg-Alzheimer's disease (AD) mice
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| EZHS42 | 04053252732133 |