FCMAB104A4
Anti-phospho H3 (Ser10) Antibody, clone 3H10 Alexa Fluor™ 488
clone 3H10, from mouse, ALEXA FLUOR™ 488
别名:
H3 histone, family 3A, H3S10P, Histone H3 (phospho S10), H3 histone, family 3A, H3 histone, family 3B, H3 histone, family 3B (H3.3B)
生物来源
mouse
质量水平
偶联物
ALEXA FLUOR™ 488
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
3H10, monoclonal
种属反应性
human
技术
flow cytometry: suitable
同位素/亚型
IgG1κ
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
phosphorylation (pSer10)
基因信息
human ... HIST1H3F(8968)
相关类别
一般描述
Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
17 kDa observed
免疫原
A proprietary immunogen based on a peptide sequence containing phospho-serine corresponding to residue 10 of human histone H3.
Epitope: Ser10
应用
Anti-Phospho-Histone H3 (Ser10) Antibody, clone 3H10, Alexa Fluor™ 488, is a Mouse Monoclonal Antibody for detection of Histone H3 phosphorylated at serine 10. This purified mAb, also known as H3S10p,
is labeled with Alexa Fluor 488 and validated for use in FC.
is labeled with Alexa Fluor 488 and validated for use in FC.
Research Category
Epigenetics & Nuclear Function
Apoptosis & Cancer
Epigenetics & Nuclear Function
Apoptosis & Cancer
Research Sub Category
Histones
Cell Cycle, DNA Replication & Repair
Histones
Cell Cycle, DNA Replication & Repair
生化/生理作用
Broad species cross-reactivity is expected.
Histone H3 phosphorylated at Ser10
外形
Protein G Purified
Purified mouse IgG1k conjugated to Alexa Fluor™ 488 in PBS with 15mg/mL BSA and less than 0.09% sodium azide.
制备说明
Maintain refrigerated at 2-8oC in undiluted aliquots for up to 6 months from date of receipt. Protect from light.
分析说明
Control
Jurkat Cells
Jurkat Cells
Evaluated by Flow Cytometry with Jurkat cells.
法律信息
ALEXA FLUOR is a trademark of Life Technologies
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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