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Merck
CN

FCMAB112F

Sigma-Aldrich

Anti-SOX-2 Antibody, clone 6G1.2, FITC conjugate

clone 6G1.2, from mouse, FITC conjugate

别名:

SRY (sex determining region Y)-box 2, SRY-related HMG-box gene 2, sex-determining region Y-box 2, transcription factor SOX2

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关于此项目

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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生物来源

mouse

质量水平

偶联物

FITC conjugate

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

6G1.2, monoclonal

种属反应性

human, rat, mouse

技术

flow cytometry: suitable

同位素/亚型

IgG2b

NCBI登记号

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... SOX2(6657)
mouse ... Sox2(20674)
rat ... Sox2(499593)

一般描述

Sox-2 plays a key role in embryonic stem cell development, and has been shown to help stem cells maintain a pluripotent potential. It has also been shown to be associated with uncommitted dividing stem cell and precursor cells of the developing CNS.
~34 kDa

应用

Anti-SOX-2 Antibody, clone 6G1.2, FITC conjugate is an antibody against SOX-2 for use in FC.

生化/生理作用

SOX-2

外形

Purified mouse monoclonal IgG2b conjugated to FITC in PBS with less than 0.09% sodium azide and 15 mg/mL BSA.

分析说明

Control
Rat Neural Stem Cells.
Evaluated by flow cytometry on undifferentiated adult Rat hippocampal neural stem cells SCR022.
Optimal working dilutions must be determined by the end user.

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储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Breanna S Borys et al.
Biotechnology and bioengineering, 117(5), 1316-1328 (2020-01-22)
Embryonic stem cells (ESCs) have almost unlimited proliferation capacity in vitro and can retain the ability to contribute to all cell lineages, making them an ideal platform material for cell-based therapies. ESCs are traditionally cultured in static flasks on a
Thalia Jimenez et al.
American journal of cancer research, 10(10), 3487-3506 (2020-11-10)
Breast cancer remains a complex disease resulting in high mortality in women. A subset of cancer stem cell (CSC)-like cells expressing aldehyde dehydrogenase 1 (ALDH1) and SOX2/OCT4 are implicated in aggressive biology of specific subtypes of breast cancer. Targeting these

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