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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.44
eCl@ss:
32160702
Conjugate:
FITC conjugate
Clone:
C3D-1, monoclonal
Application:
flow cytometry
Species reactivity:
human
Citations:
2
Technique(s):
flow cytometry: suitable
Uniprot accession no.:
产品名称
Milli-Mark® Anti-CD15-FITC Antibody, clone C3D-1, clone C3D-1, Milli-Mark®, from mouse
biological source
mouse
conjugate
FITC conjugate
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
C3D-1, monoclonal
species reactivity
human
manufacturer/tradename
Milli-Mark®
technique(s)
flow cytometry: suitable
isotype
IgMκ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... FUT4(2526)
Analysis Note
Evaluated by flow cytometry using human PBMCs
Application
This Milli-Mark Anti-CD15-FITC Antibody, clone C3D-1 is validated for use in FC for the detection of CD15.
Biochem/physiol Actions
Antibody recognizes Human CD15 antigen.
General description
CD15 is a carbohydrate antigen carried by both glycoproteins and glycoliplds. The structure of the antigen was determined to be Galb1→4[Fuca1→3]GIcNACb1→3Galb1→R. CD15 serves as a ligand for selectins and might also be involved in cell adhesion through a direct Lewis X-Lewis X interaction. CD15 is expressed mainly on mature granulocytes and monocytes but also on immature bone marrow cells (Kannagi, 1997).
Anti-CD15, C3D-1, was included in the Sixth International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD15 (Kannagi, 1997).
Anti-CD15, C3D-1, was included in the Sixth International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD15 (Kannagi, 1997).
Immunogen
Purified human neutrophils
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Activated Sepharose
Purified Mouse monoclonal IgM conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
Legal Information
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Glioblastoma (GBM), a highly aggressive brain tumor, contains a subpopulation of glioblastoma stem-like cells (GSCs) that play roles in tumor maintenance, invasion, and therapeutic resistance. GSCs are therefore a promising target for GBM treatment. Our group identified the cellular prion
Marlieke L M Jongsma et al.
Immunity, 54(1), 132-150 (2020-12-04)
HLA class I (HLA-I) glycoproteins drive immune responses by presenting antigens to cognate CD8+ T cells. This process is often hijacked by tumors and pathogens for immune evasion. Because options for restoring HLA-I antigen presentation are limited, we aimed to identify
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