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Merck
CN

FCMAB291F

Milli-Mark®Anti-Cytokeratin 5 Antibody, 6-FITC, clone D5/16B4

clone D5/16B4, Milli-Mark®, from mouse

别名:

58 kDa cytokeratin, epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types, keratin 5, keratin 5 (epidermolysis bullosa simplex,Dowling-Meara/Kobner/Weber-Cockayne types), keratin, type II cytoskeletal 5

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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产品名称

Milli-Mark®Anti-Cytokeratin 5 Antibody, 6-FITC, clone D5/16B4, clone D5/16B4, Milli-Mark®, from mouse

biological source

mouse

conjugate

FITC conjugate

antibody form

purified antibody

antibody product type

primary antibodies

clone

D5/16B4, monoclonal

species reactivity

human

manufacturer/tradename

Milli-Mark®

technique(s)

flow cytometry: suitable

isotype

IgG1κ

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... KRT5(3852)

Analysis Note

Control
A431 cells
Evaluated by flow cytometry using A431 cells

Application

Milli-MarkAnti-Cytokeratin 5 Antibody, 6-FITC, clone D5/16B4 is an antibody against Cytokeratin 5 for use in FC.
Research Category
Cell Structure
Research Sub Category
Cytoskeleton

Biochem/physiol Actions

Antibody recognizes Human Cytokeratin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

The calculated for Cytokeratin is 62 kDa, however, different isoforms state Cytokeratin 4 (59 kDa), Cytokeratin 5 (58 kDa) and Cytokeratin 6 (56 kDa).
The cytokeratins are a family of intermediate filaments found in almost all epithelial cells. They are divided into four subclasses depending on their patterns of reactivity and electrophoretic characteristics and are also arranged I a numbered series of 20 or more acoring to molecular weight and isoelectric point (Quinlan et al. 1985). Types 5 and 6 of cytokeratin (CK5/6) are in high frequency in mesothelial cells, as opposed to cells of adenocarcinoma. CK5/6 has been shown to be a reliable marker for mesothelioma and squamous cell carcinoma of the lung and Bowen′s disease. It does not react with pulmonary adenocarcinoma.

Immunogen

Purified cytokeratin 5 (Wild, 1986) (Mischke, 1987).

Physical form

Protein A purified
Purified mouse monoclonal IgG1 conjugated to FITC in PBS buffer with 15mg/mL BSA and sodium azide at 0.1%.

Preparation Note

Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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