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Merck
CN

FCMAB313PE

Milli-Mark® Anti-Nestin-PE Antibody, clone 10C2

clone 10C2, Milli-Mark®, from mouse

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
PE
Clone:
10C2, monoclonal
Application:
flow cytometry
Species reactivity:
human
Citations:
1
Technique(s):
flow cytometry: suitable
Uniprot accession no.:
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产品名称

Milli-Mark® Anti-Nestin-PE Antibody, clone 10C2, clone 10C2, Milli-Mark®, from mouse

biological source

mouse

conjugate

PE

antibody form

purified antibody

antibody product type

primary antibodies

clone

10C2, monoclonal

species reactivity

human

should not react with

mouse, rat

manufacturer/tradename

Milli-Mark®

technique(s)

flow cytometry: suitable

isotype

IgG1κ

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... NES(10763)

Analysis Note

Evaluated by flow cytometry using U251 cells.

Application

Detect Nestin using this Milli-Mark Anti-Nestin-PE Antibody, clone 10C2 validated for use in FC.

Biochem/physiol Actions

Antibody recognizes Human Nestin.

General description

Nestin, a large intermediate filament protein (class Type VI) expressed during development and in myotendinous and neuromuscular junctions. Nestin expression is restricted, typically disappearing by E18. Nestin is thought to be a reasonable neuronal marker; however, recent studies have found nestin expression in other cell types such as endothelial cells {Folia Biologica, 44(5):155, 1998}. Nestin identifies the most primitive neuroepithelium but also identifies many other embryonic tissues, so it is not specific for CNS. Nestin expression is seen in almost all GBMs (Glioblastoma mulitformes) and many melanomas (both primary and metastatic) but not in any metastatic carcinoma.
177 kDa Calculated

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Polina A Vishnyakova et al.
Scientific reports, 6, 32410-32410 (2016-08-31)
Preeclampsia (PE) is a pregnancy-specific syndrome, characterized in general by hypertension with proteinuria or other systemic disturbances. PE is the major cause of maternal and fetal morbidity and mortality worldwide. However, the etiology of PE still remains unclear. Our study

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