生物来源
mouse
质量水平
偶联物
FITC conjugate
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
H11-4, monoclonal
种属反应性
human
制造商/商品名称
Milli-Mark®
技术
flow cytometry: suitable
同位素/亚型
IgG1
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... H3C1(8350)
一般描述
Antibody recognizes histones H1, H2A, H2B, H3, and H4. Calculated molecular weight for these histones range from 14 to 21 kDa
There are 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. The five major classes of histones are H1/H5, H2A, H2B, H3, and H4. Histones H2A, H2B, H3 and H4 are known as the core histones, while histones H1 and H5 are known as the linker histones. Histones feature a main globular domain and a long N terminal tail which are involved with the structure of the nucleosomes of the ′beads on a string′ structure. They are the chief protein components of chromatin, acting as spools around which DNA winds, and play a role in gene regulation.
应用
This Milli-Mark Anti-pan Histone-FITC Antibody, clone H11-4 is validated for use in FC for the detection of pan Histone.
生化/生理作用
Due to the highly conserved nature of histones, this antibody is predicted to have wide species reactivity.
分析说明
Evaluated by flow cytometry using HeLa cells.
法律信息
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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