IL-28B, Human

HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.

IL-28B is a cytokine distantly related to type I interferons and the IL-10 family. IL-28A, IL-28B, and IL-29 are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).

Product is presented in PBS and filtered through a 0.2 micron filter before lyophilization.

Store at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added.

Bioactivity assay: Determined by the dose dependent protection of the cytopathic effect on A549 cells (human lung
adenocarcinoma epithelial cell line) that were challenged with encephalomyocarditis (EMC) virus. ED50 is typically 0.1-1 ng/ml.

HumanKine IL-28B is manufactured using all non-animal reagents and is considered Xeno-Free

HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.