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HADCYMAG-61K

MILLIPLEX® Human Adipocyte Panel

Configurable Human Adipocyte 11-Plex Panel

别名:

adipocyte biomarker listing, adipokine assay snapshot, adipokine biomarker profile, adipokine detection kit, adipokine multiplex product sheet, adipose tissue biomarker details, human adipocyte assay overview, human adipocyte panel summary, human adipokine product info, human adipokine research tool

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关于此项目

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

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species reactivity

human

Quality Level

200

assay range

accuracy: 100%
(IL-6), accuracy: 102%
(TNFα), accuracy: 103%
(MCP-1), accuracy: 83%
(PAI-1 (total)), accuracy: 99%
(HGF), sensitivity: 0.2 pg/mL
(MinDC+2SD; IL-8), sensitivity: 0.2 pg/mL
(MinDC+2SD; NGF), sensitivity: 0.2 pg/mL
(MinDC+2SD; TNF?), sensitivity: 0.6 pg/mL
(MinDC+2SD; IL-6), sensitivity: 10 pg/mL
(MinDC+2SD; Leptin), sensitivity: 15 pg/mL
(MinDC+2SD; Adiponectin), sensitivity: 2.0 pg/mL
(MinDC+2SD; IL-1?), sensitivity: 2.1 pg/mL
(MinDC+2SD; MCP-1), sensitivity: 3.0 pg/mL
(MinDC+2SD; HGF), sensitivity: 4.4 pg/mL
(MinDC+2SD; Resistin), sensitivity: 4.6 pg/mL
(MinDC+2SD; PAI-1 (total)), standard curve range: 0.29-4,000 pg/mL
(IL-8), standard curve range: 0.32-5,000 pg/mL
(NGF), standard curve range: 0.38-6,000 pg/mL
(TNFα), standard curve range: 0.51-8,000 pg/mL
(IL-1β), standard curve range: 0.96-150,000 pg/mL
(IL-6), standard curve range: 0.96-150,000 pg/mL
(MCP-1), standard curve range: 26-400,000 pg/mL
(Adipnectin), standard curve range: 6.4-100,000 pg/mL
(HGF), standard curve range: 6.4-100,000 pg/mL
(Resistin), standard curve range: 9.6-150,000 pg/mL
(Leptin), standard curve range: 9.6-150,000 pg/mL
(PAI-1), inter-assay cv: <15%
intra-assay cv: <10%
(Adiponectin), inter-assay cv: <15%
intra-assay cv: <10%
(IL-8), inter-assay cv: <15%
intra-assay cv: <10%
(MCP-1), inter-assay cv: <15%
intra-assay cv: <10%
(Resistin), inter-assay cv: <20%
intra-assay cv: <10%
(HGF), inter-assay cv: <20%
intra-assay cv: <10%
(IL-6), inter-assay cv: <20%
intra-assay cv: <10%
(NGF), inter-assay cv: <20%
intra-assay cv: <10%
(PAI-1 (total)), inter-assay cv: <20%
intra-assay cv: <10%
(TNFα), inter-assay cv: <20%
intra-assay cv: <15%
(IL-1β), inter-assay cv: <25%
intra-assay cv: <20%
(Leptin)

technique(s)

multiplexing: suitable

input

cell culture supernatant

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

相关类别

Features and Benefits

Features: Targets key adipokines and cytokines involved in metabolic and inflammatory processes Includes 11 analytes relevant to adipocyte function, inflammation, and energy homeostasis Multiplex format enables simultaneous detection from minimal sample volume Compatible with human cell culture supernatants and tissue extracts Designed for research in obesity, insulin resistance, and metabolic syndrome
Benefits: Provides a comprehensive profile of adipocyte-derived signaling molecules Supports investigation of inflammation and metabolic dysregulation in human models Facilitates evaluation of therapeutic interventions targeting adipose tissue function Enables high-throughput analysis with reduced sample and reagent use Delivers reproducible, sensitive results for translational and preclinical research

General description

Adipose tissue plays a central role in metabolic regulation and inflammation. This set of biomarkers includes Adiponectin, HGF, IL-1β, IL-6, IL-8/CXCL8, Leptin, MCP-1/CCL2, NGF, PAI-1 (total), Resistin, and TNFα, which are key mediators of adipocyte function and immune signaling. These analytes provide insights into processes such as insulin sensitivity, lipid metabolism, inflammatory response, and adipose tissue remodeling. Their measurement supports research into obesity, metabolic syndrome, type 2 diabetes, and related inflammatory conditions.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 11 analytes in human cell or tissue culture supernatants.

Analytes included: Adiponectin, HGF, IL-1β, IL-6, IL-8/CXCL8, Leptin, MCP-1/CCL2, NGF, PAI-1 (total), Resistin, TNFα

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

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Tracey McLaughlin et al.
Journal of the American Heart Association, 10(22), e021003-e021003 (2021-11-03)
Background Inflammation in epicardial adipose tissue (EAT) may contribute to coronary atherosclerosis. Myocardial bridge is a congenital anomaly in which the left anterior descending coronary artery takes a "tunneled" course under a bridge of myocardium: while atherosclerosis develops in the
Katharina Kessler et al.
Nutrients, 12(2) (2020-02-06)
: Meal timing affects metabolic regulation in humans. Most studies use blood samples for their investigations. Saliva, although easily available and non-invasive, seems to be rarely used for chrononutritional studies. In this pilot study, we tested if saliva samples could
Jelizaveta Sokolovska et al.
Physiological reports, 8(13), e14506-e14506 (2020-07-12)
Interval walking training has demonstrated more pronounced positive effects on physical fitness and metabolism in type 2 diabetes (T2D), compared to continuous walking. One of the pathogenic mechanisms of T2D is associated with derangements in leptin/adiponectin axis, which might predispose
Sonja Suvakov et al.
EBioMedicine, 70, 103536-103536 (2021-08-15)
Preeclampsia is a pregnancy-specific hypertensive disorder characterized by proteinuria and/or multisystem involvement. Disease-specific therapy has yet to be developed due to the lack of understanding of underlying mechanism(s). We postulate that accelerated ageing in general, and particularly cellular senescence, play
Pilar Codoñer-Franch et al.
Clinical biochemistry, 47(1-2), 44-48 (2013-11-05)
To evaluate whether serum resistin levels are related to cardiovascular risk in obese children. Cross-sectional study of 110 children (40 normal weight and 70 severely obese). Clinical and biochemical parameters, including lipid profile, fasting glucose and insulin, and homocysteine, were
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相关内容

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Multiplex immunoassays, such as MILLIPLEX® multiplex metabolic assays, are critical in metabolic syndrome research because they provide a full picture of the different conditions related to it, like diabetes and obesity, as well as save time and sample volume.

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Quality Control Ranges: Human Adipocyte Magnetic Bead Panel -HADCYMAG-61K
96 well Template Single
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