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Merck
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HADK1MAG-61K

MILLIPLEX® Human Adipokine Panel

Configurable Human Adipokine 5-Plex Panel 1

别名:

adipocyte biomarker listing, adipokine assay snapshot, adipokine biomarker profile, adipokine detection kit, adipokine multiplex product sheet, adipose tissue biomarker details, human adipokine assay overview, human adipokine panel summary, human adipokine product info, human adipokine research tool

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UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000

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产品名称

MILLIPLEX® Human Adipokine Panel, Configurable Human Adipokine 5-Plex Panel 1

Quality Level

200

species reactivity

human

manufacturer/tradename

Milliplex®

description

packaging

1 ea of

assay range

accuracy: 87%
(Resistin)
accuracy: 89%
(Adiponectin)
sensitivity: 10 pg/mL
(MinDC+2SD; Adipsin)
sensitivity: 21 pg/mL
(MinDC+2SD; Adiponectin)
sensitivity: 3.5 pg/mL
(MinDC+2SD; Lipocalin-2/NGAL)
sensitivity: 4.4 pg/mL
(MinDC+2SD; Resistin)
sensitivity: 5.8 pg/mL
(MinDC+2SD; PAI-1)
standard curve range: 13-200,000 pg/mL
(Adipsin)
standard curve range: 26-400,000 pg/mL
(Adiponectin)
standard curve range: 3.2-50,000 pg/mL
(Lipocalin-2/NGAL)
standard curve range: 6.4-100,000 pg/mL
(Resistin)
standard curve range: 9.6-150,000 pg/mL
(PAI-1 (total))
inter-assay cv: <10%
intra-assay cv: <10%
(Adipsin)
inter-assay cv: <10%
intra-assay cv: <15%
(Adiponectin)
inter-assay cv: <10%
intra-assay cv: <15%
(Lipocalin-2/NGAL)
inter-assay cv: <10%
intra-assay cv: <20%
(PAI-1 (total))
inter-assay cv: <10%
intra-assay cv: <20%
(Resistin)

technique(s)

multiplexing: suitable

input

serum plasma

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

相关类别

Features and Benefits

Design your multiplex kit by choosing available analytes within this panel.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

General description

Adipokines are bioactive proteins secreted by adipose tissue that play key roles in metabolic regulation, inflammation, and energy homeostasis. This set of biomarkers—Adiponectin, Adipsin (Factor D), NGAL/Lipocalin-2, PAI-1 (total), and Resistin—provides valuable insights into adipocyte function and systemic metabolic health. These analytes are associated with insulin sensitivity, lipid metabolism, immune response, and cardiovascular risk, making them highly relevant for research in obesity, diabetes, and related metabolic disorders.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 5 analytes in human serum or plasma samples.

Analytes included: Adiponectin, Adipsin/Factor D, NGAL/Lipocalin-2, PAI-1 (total), Resistin

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

法规信息

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Emily Eruysal et al.
Alzheimer's & dementia (Amsterdam, Netherlands), 11, 646-653 (2019-09-14)
Lipocalin-2 is an acute-phase protein with pleotropic functions that has been implicated in several diseases including Alzheimer's disease (AD). However, it is unknown if circulating lipocalin-2 levels are altered in the preclinical stage of AD, where AD pathology has accumulated
Ingrid V Hagen et al.
The British journal of nutrition, 116(4), 648-657 (2016-07-02)
The aim of the present study was to examine whether high intake of lean or fatty fish (cod and farmed salmon, respectively) by healthy, normal-weight adults would affect risk factors of type 2 diabetes and CVD when compared with lean
Diana Silva et al.
PloS one, 14(4), e0215475-e0215475 (2019-04-19)
Adipose tissue-derived adipokines are pro-inflammatory cytokines involved in metabolic-related diseases and can be influenced by diet and exercise. We aimed to compare the effect of a Mediterranean (MdM) compared with Fast Food (FFM) meal on the exercise induced adipokines changes.
A pilot study of active vitamin D administration and insulin resistance in African American patients undergoing chronic hemodialysis.
Hung, AM; Sundell, MB; Plotnikova, NE; Bian, A; Shintani, A; Ellis, CD; Siew, ED; Ikizler, TA
Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation null
Ida Heir Hovland et al.
European journal of nutrition, 59(3), 1013-1029 (2019-04-12)
To examine whether supplementation with low doses of fish or milk proteins would affect glucose regulation and circulating lipid concentrations in overweight healthy adults. Ninety-three overweight adults were assigned to receive 2.5 g protein/day from herring (HER), salmon (SAL), cod (COD)
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