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HBNMAG-51K

MILLIPLEX® 人骨磁珠板 - 骨代谢多重检测

Configurable Human Bone 13-Plex Panel

别名:

human bone metabolic biomarkers immunoassay panel, luminex human bone metabolism multiplex assay, millipore human bone metabolic biomarkers multiplex kit, bone turnover assay overview, human bone biomarker panel, human bone metabolism assay, inflammation and bone health panel, skeletal disease multiplex kit

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关于此项目

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000
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产品名称

MILLIPLEX® 人骨磁珠板 - 骨代谢多重检测, Configurable Human Bone 13-Plex Panel

species reactivity

human

manufacturer/tradename

Milliplex®

Quality Level

packaging

1 ea of

assay range

accuracy: 82-97%
standard curve range: 0.24-1,000 pg/mL
(TNFα)

standard curve range: 1-3,000 pg/mL
(IL-1β)

standard curve range: 1-6,000 pg/mL
(ACTH & IL-6)

standard curve range: 146-600,000 pg/mL
(OC)

standard curve range: 24-100,000 pg/mL
(SOST)

standard curve range: 37-150,000 pg/mL
(FGF-23)

standard curve range: 49-200,000 pg/mL
(Leptin)

standard curve range: 5-20,000 pg/mL
(DKK-1)

standard curve range: 5-20,000 pg/mL
(PTH)

standard curve range: 61-250,000 pg/mL
(Insulin)

standard curve range: 7-30,000 pg/mL
(OPG)

standard curve range: 98-400,000 pg/mL
(OPN)

technique(s)

multiplexing: suitable

input

serum plasma (cell culture supernatants, tissue/cell extracts)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Biochem/physiol Actions

交叉反应
对于该面板中的分析物,未观察到抗体之间的交叉反应性。

Features and Benefits

通过在此面板中选择可用的分析物来设计多重试剂盒。

Other Notes

替代:HBN1B-51K

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

General description

Bone health is regulated by a complex interplay of hormonal, inflammatory, and metabolic signals. This panel—ACTH, DKK1, FGF-23, IL-1β, IL-6, Insulin, Leptin, Osteocalcin (OC), Osteopontin (OPN), Osteoprotegerin (OPG), PTH, Sclerostin (SOST), and TNFα—captures key indicators of bone remodeling, endocrine function, and immune activity. These analytes are valuable for studying osteoporosis, arthritis, and metabolic bone diseases, supporting both translational and clinical research in skeletal biology.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 13 analytes in human serum, plasma, or cell/tissue culture supernatants.

Analytes Included: ACTH, DKK1, FGF-23, IL-1β, IL-6, Insulin, Leptin, Osteocalcin (OC), Osteopontin (OPN), Osteoprotegerin (OPG), PTH, Sclerostin (SOST), TNFα

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

法规信息

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Edward R Smith et al.
Scientific reports, 7(1), 5686-5686 (2017-07-20)
Calciprotein particles, nanoscale aggregates of insoluble mineral and binding proteins, have emerged as potential mediators of phosphate toxicity in patients with Chronic Kidney Disease. Although existing immunochemical methods for their detection have provided compelling data, these approaches are indirect, lack
Sharon M Moe et al.
Circulation, 132(1), 27-39 (2015-06-11)
Patients with kidney disease have disordered bone and mineral metabolism, including elevated serum concentrations of fibroblast growth factor-23 (FGF23). These elevated concentrations are associated with cardiovascular and all-cause mortality. The objective was to determine the effects of the calcimimetic cinacalcet
Nigel Kurgan et al.
Frontiers in endocrinology, 11, 531926-531926 (2020-12-29)
In adults, excess adiposity has been associated with low-grade, chronic inflammation and compromised bone health, but less is known about these linkages in children. The purpose of this study was to compare the circulating levels of inflammatory cytokines, adipokines, osteokines
Chia-Liang Tsai et al.
Experimental physiology, 102(12), 1683-1699 (2017-10-07)
What is the central question of this study? Obesity is linked to cognitive deficits, elevated energy metabolic indices and low-grade systemic inflammation. Do the relationships between neurocognitive performance and the biochemical markers (e.g. energy metabolic indices and inflammatory cytokines) occur
Tsang-Hai Huang et al.
Journal of musculoskeletal & neuronal interactions, 20(2), 206-215 (2020-06-03)
The present study determined time-course changes in plasma bone-specific and -related markers following a bout of maximal eccentric contractions (MaxEC) of bilateral knee extensors (KE) and flexors (KF). Sedentary young men (n=30) performed a bout of 10 sets of 10

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