HCCB4MAG-58K

MILLIPLEX^® Human Circulating Cancer Biomarker Panel

Name: MILLIPLEX<SUP>®</SUP> Human Circulating Cancer Biomarker Panel
Brand: MM

Configurable Human Circulating Cancer Biomarker 10-Plex Panel 4

别名:

Luminex human circulating cancer biomarkers multiplex assay, Millipore human circulating cancer biomarkers multiplex kit, human cancer biomarker immunoassay panel

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关于此项目

UNSPSC Code:

12161503

NACRES:

NA.84

eCl@ss:

32161000

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产品名称

MILLIPLEX^® Human Circulating Cancer Biomarker Panel, Configurable Human Circulating Cancer Biomarker 10-Plex Panel 4

Quality Level

200

species reactivity

human

manufacturer/tradename

Milliplex^®

packaging

1 ea of

assay range

accuracy: 80-110%
standard curve range: 0.1-100 ng/mL
(L1CAM)
standard curve range: 0.1-100 ng/mL
(Mesothelin)
standard curve range: 0.3-250 ng/mL
(Hepsin)
standard curve range: 1.4-1,000 ng/mL
(CD44)
standard curve range: 1.4-1,000 ng/mL
(Transglutaminase 2 (TGM2))
standard curve range: 13.7-10,000 pg/mL
(EpCAM)
standard curve range: 13.7-10,000 pg/mL
(Midkine)
standard curve range: 2.7-2,000 ng/mL
(ALDH1A1)
standard curve range: 20.6-15,000 pg/mL
(Carbonic Anhydrase IX (CA9))
standard curve range: 27.4-20,000 pg/mL
(Kallekrein-6)
inter-assay cv: <10%
intra-assay cv: <20%

technique(s)

multiplexing: suitable

input

serum plasma (Cell culture, cell culture supernatants)

detection method

fluorometric (Luminex^® xMAP^® technology)

shipped in

wet ice

storage temp.

2-8°C

Legal Information

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Versatile 10-Plex Analyte Kit: This panel allows for the simultaneous quantification of ten significant biomarkers, including ALDH1A1, CA9, and CD44, providing a broad scope for cancer research.
Diverse Sample Compatibility: Suitable for human serum, plasma, and tissue culture supernatants, allowing flexibility in sample types for various research applications.
Recommended Sample Dilution: The assay suggests using 25 μL of 1:5 diluted serum or plasma, with tissue culture supernatants requiring appropriate dilution, simplifying the preparation process.
Comprehensive Insights into Tumor Dynamics: By enabling the simultaneous measurement of multiple circulating biomarkers, this panel aids researchers in exploring the complex interactions between tumors and their microenvironment.
Increased Efficiency in Research: The multiplex capability allows for a significant boost in sample throughput, enabling researchers to analyze a larger number of samples in less time, which is crucial for high-volume research.

General description

Circulating cancer biomarkers give insight beyond intracellular oncogenesis and into how the body responds to the presence of a tumor, the dysregulation of homeostasis, and the relationship between a tumor and its environment. Multianalyte panels have become essential tools that enable researchers to measure cancer biomarkers simultaneously, teasing out these relationships and applying them to understand tumor biology.

Application

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 10 analytes in human serum, plasma, and cell culture supernatants.

Analytes included: Aldheyde dehydrogenase 1 Family, Member A1 (ALDH1A1), Carbonic Anhydrase IX (CA9), CD44, Epithelial cell adhesion molecule (EpCAM), Hepsin, Kallikrein-6, Mesothelin, Midkine, Neural cell adhesion Molecule L1 (L1CAM), Transglutaminase 2 (TGM2)

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

pictograms

GHS06,GHS08,GHS05,GHS09

signalword

Danger

hcodes

H302 + H332,H311,H317,H318,H373,H411

pcodes

P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

wgk

WGK 3

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Development of bead based multiplexed immunoassay for evaluation of midkine, syndecan-1, and ANGPTL4 in patient serum.

Imad Tarhoni et al.

Journal of immunoassay & immunochemistry, 39(1), 84-98 (2018-01-09)

Angiogenesis is associated with tumor progression in a range of malignancies. Herein, we develop custom immunobead assays for several mechanistically important targets and evaluated these against sera from cohorts of non-small cell lung cancer (NSCLC) patients. Antigen "capture" antibodies for

MILLIPLEX® Human Circulating Cancer Biomarker Panel