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Merck
CN

HCCBP3MAG-58K

MILLIPLEX® 人循环癌症生物标志物磁珠板3 - 癌症多重检测

Configurable Human Circulating Cancer Biomarker 8-Plex Panel 3

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关于此项目

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000
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产品名称

MILLIPLEX® 人循环癌症生物标志物磁珠板3 - 癌症多重检测, Configurable Human Circulating Cancer Biomarker 8-Plex Panel 3

species reactivity

human

manufacturer/tradename

Milliplex®

Quality Level

packaging

1 ea of

assay range

accuracy: 74-126%
standard curve range: 0.004-3 ng/mL
(Galectin-3)

standard curve range: 0.02-20 ng/mL
(Myeloperoxidase)

standard curve range: 0.03-25 nM
(Sex Hormone Binding Globulin)

standard curve range: 0.03-25 ng/mL
(Ferritin)

standard curve range: 0.07-50 ng/mL
(Catalase, Fibroblast Activation Protein α)

standard curve range: 0.1-75 ng/mL
(Melanoma Inhibitory Activity Protein)

standard curve range: 0.27-200 ng/mL
(Cathepsin D, IGFBP3)

technique(s)

multiplexing: suitable

input

serum plasma (Cell culture, cell culture supernatants)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Legal Information

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Luminex is a registered trademark of Luminex Corp

Analysis Note

根据WHO标准品08/266校准SHBG标准品,250 ng/mL标准品相当于25 nM WHO标准品

Biochem/physiol Actions

交叉反应性
抗体与该面板中任何其他分析物之间的交叉反应性都为无法检测或可忽略。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

通过在此面板中选择可用的分析物来设计多重试剂盒。

General description

循环中的癌症生物标志物不仅可以洞察细胞内的肿瘤发生,还可以洞察人体对肿瘤的存在,体内稳态失调以及肿瘤与其环境之间的关系的反应。多分析物面板已成为使研究人员能够同时测量癌症生物标志物,弄清这些关系并将其应用于了解肿瘤生物学的重要工具。

MILLIPLEX®人循环生物标记物检测板3是一种8重试剂盒,用于同时定量或全部血清、血浆和组织/细胞裂解物以及培养上清液样品中的以下分析物: Galectin-3,组织蛋白酶D,成纤维细胞活化蛋白α(FAP),黑色素瘤抑制活性蛋白(MIA),髓过氧化物酶,性激素结合球蛋白(SHBG),胰岛素样生长因子结合蛋白3(IGFBP3)和铁蛋白。该试剂盒采用96孔板,包含冻干标准混合物、两个内部检测质控品,可最多可测定38份样本,重复两次。

Luminex® xMAP®平台使用磁珠免疫分析格式,以实现理想的速度和灵敏度,同时定量多种分析物,从而显著提高生产力,同时节省宝贵的样本量。

面板类型:循环癌症
Circulating cancer biomarkers give insight beyond intracellular oncogenesis and into how the body responds to the presence of a tumor, the dysregulation of homeostasis, and the relationship between a tumor and its environment. Multianalyte panels have become essential tools that enable researchers to measure cancer biomarkers simultaneously, teasing out these relationships and applying them to understand tumor biology.

Packaging

单个试剂盒即可满足您的所有需求。

Preparation Note

试剂盒组分建议的存储温度为2-8°C。

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 8 analytes in human serum, plasma, and cell culture supernatants.Analytes included: Cathepsin D, Ferritin, Fibroblast Activation Protein (FAP), Galectin-3, IGFBP3, Melanoma Inhibitory Activty Protein (MIA), Myeloperoxidase (MPO), Sex Hormone Binding Globulin (SHGB)Note: When IGFBP3 is included in the assay, a larger sample dilution is required. The SHBG Standard was calibrated against WHO standard 08/266 and 250 ng/mL standard was equivalent to 25 nM of WHO standard.Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

pictograms

Skull and crossbonesEnvironment

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

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Juan Pablo Hinestrosa et al.
Communications medicine, 2, 29-29 (2022-05-24)
Detecting cancer at early stages significantly increases patient survival rates. Because lethal solid tumors often produce few symptoms before progressing to advanced, metastatic disease, diagnosis frequently occurs when surgical resection is no longer curative. One promising approach to detect early-stage

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Cancer biomarker detection through MILLIPLEX® multiplex cancer assays can accelerate studies of tumorigenic processes helping advance cancer research.

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