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Merck
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HCYP2MAG-62K

MILLIPLEX® 人细胞因子/趋化因子磁珠板II - 免疫学多重分析

Simultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in human serum, plasma and cell culture samples.

别名:

Human cytokine multiplex kit, Luminex® human cytokine immunoassay, Millipore human cytokine panel

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关于此项目

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

主要文件

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产品名称

MILLIPLEX® 人细胞因子/趋化因子磁珠板II - 免疫学多重分析, Simultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in human serum, plasma and cell culture samples.

species reactivity

human

manufacturer/tradename

Milliplex®

assay range

accuracy: 81-110%
sensitivity: 0.4-55.8 pg/mL
standard curve range: 1.0-100,000 pg/mL

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex xMAP)

shipped in

wet ice

Quality Level

200

相关类别

Application

  • 分析物：6Ckine, BCA-1, CTACK, ENA-78, Eotaxin-2, Eotaxin-3, I-309, IL-16, IL-20, IL-21, IL-23, IL-28A, IL-33, LIF, MCP-2, MCP-4, MIP-1δ, SCF, SDF-1A+β, TARC, TPO, TRAIL, TSLP
  • 推荐的样品类型：血清，血浆和细胞培养上清液
  • 推荐的样品稀释度：未稀释
  • 分析运行时间：过夜或2小时初次孵育。为了获得最佳结果，建议过夜孵育
  • 研究类别：炎症 & 免疫学
  • 研究子类别：肥胖，代谢紊乱，炎症 & 自身免疫机制

Biochem/physiol Actions

交叉反应性
对于该面板中的任何其他分析物，抗体之间没有或有可以忽略不计的交叉反应性。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

Features and Benefits

通过在此面板中选择可用的分析物来设计多重试剂盒。

General description

“细胞因子”是用于多种可溶性蛋白质和肽的通用术语，其在正常和病理条件下充当调节剂以调节单个细胞和组织的功能活性。这些蛋白质还介导细胞之间的直接各种相互作用并调节细胞外环境中发生的过程。细胞因子组蛋白包括淋巴因子、干扰素、集落刺激因子和趋化因子。细胞因子和趋化因子研究对于更深入地了解免疫系统及其对大多数抗原的多方面反应以及疾病状态（例如炎症性疾病，过敏反应，肠易激综合征（IBD），脓毒症和癌症）具有重要作用。

MILLIPLEX®人细胞因子/趋化因子面板II使您能够专注于细胞因子的治疗潜力以及细胞因子表达的调节。

Luminex® xMAP®平台使用磁珠免疫分析格式，以实现理想的速度和灵敏度，同时定量多种分析物，从而显著提高生产力，同时节省宝贵的样本量。

面板类型：细胞因子/趋化因子

Other Notes

请联系技术服务部进行稀释度线性研究。

Packaging

96孔板

Preparation Note

试剂盒组分建议的存储温度为2-8°C。

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

存储类别

10 - Combustible liquids

法规信息

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Fawaz Y Azizieh et al.
Journal of inflammation research, 12, 99-108 (2019-05-24)
Objective: In addition to some well-characterized bone turnover markers (BTMs), cytokines and adipokines have also been suggested to be linked to osteoporosis seen in menopause. However, there is much controversy on the possible association between these markers and bone mineral density
Evidence of enhanced systemic inflammation in stable kidney transplant recipients with low Framingham risk scores.
Mansell, H; Rosaasen, N; Dean, J; Shoker, A
Clinical Transplantation null
Beatriz M Carreno et al.
The Journal of clinical investigation, 123(8), 3383-3394 (2013-07-23)
Systemic administration of IL-12p70 has demonstrated clinical activity in cancer patients, but dose-limiting toxicities have hindered its incorporation in vaccine formulations. Here, we report on the immunological and clinical outcomes upon vaccination with CD40L/IFN-γ-matured, IL-12p70-producing DCs. 7 HLA-A*0201+ newly diagnosed
Carsten U Niemann et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 22(7), 1572-1582 (2015-12-15)
Chronic lymphocytic leukemia (CLL) cells depend on microenvironmental interactions for proliferation and survival that are at least partially mediated through B-cell receptor (BCR) signaling. Ibrutinib, a Bruton tyrosine kinase inhibitor, disrupts BCR signaling and leads to the egress of tumor
Myung-Ho Kim et al.
medRxiv : the preprint server for health sciences (2021-03-25)
We analyzed the plasma levels of interferons and cytokines, and the expression of interferon-stimulated genes in peripheral blood mononuclear cells in COVID-19 patients with different disease severity. Mild patients exhibited transient type I interferon responses, while ICU patients had prolonged
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相关内容

MAGPIX®and Luminex 200™ - Multiplex Detection of Inflammation Pathway Analytes

"Multiplex detection is a highly efficient tool for measuring the levels of multiple analytes in a single sample. MILLIPLEX® MAP assay panels provide a complete solution for multiplex detection of analytes within particular research areas using the bead-based Luminex® xMAP® technology. Previously, the only option for analyzing MILLIPLEX® MAP assays required the Luminex 200™ or FLEXMAP 3D® analyzers. With the launch of the MAGPIX® system, MILLIPLEX® MAP magnetic bead assays can be analyzed without the use of lasers or hydrodynamic focusing. The MAGPIX® instrument is a compact, cost-effective multiplexing system based on CCD imaging technology. The MAGPIX® instrument was specifically designed to yield comparable results to the Luminex 200™ instrument. To demonstrate similarity between the two systems, we ran parallel assays using the MILLIPLEX® MAP Human Cytokine/Chemokine Magnetic Bead Panel. Standard curve median fluorescence intensity (MFI) and sample range data are similar between the two instrument systems. Furthermore, sample concentration data between the MAGPIX® and Luminex 200™ systems demonstrate correlation coefficients ≥ 0.97."

Quality Control Range Sheet- HCYP2-115 and HCYP2-215
The Power of Biomarker Analysis
Protocol- HCYP2MAG-62K|HCP2MAG-62K-PX23|HCP2MAG62KPX23BK
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