Name: MILLIPLEX<SUP>®</SUP> Human Kidney Injury Magnetic Bead Panel 2 - Toxicity Multiplex Assay
Brand: MM

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About This Item

UNSPSC代码:

12161503

eCl@ss:

32161000

NACRES:

NA.84

质量水平

200

种属反应性

human

制造商/商品名称

Milliplex^®

assay range

accuracy: 95-109%
sensitivity: 0.015-5.359 ng/mL
(MinDC = 2SD)
standard curve range: 0.01-10 ng/mL
(EGF)
standard curve range: 0.02-20 ng/mL
(Lipocalin-2/ NGAL)
standard curve range: 0.20-200 ng/mL
(Cystatin C)
standard curve range: 0.59-600 ng/mL
(Osteopontin (OPN))
standard curve range: 0.98-1,000 ng/mL
(α-1-Microglobulin)
standard curve range: 3.91-4,000 ng/mL
(Albumin)
standard curve range: 4.88-5,000 ng/mL
(Clusterin)
inter-assay cv: <20%
intra-assay cv: <10%

技术

multiplexing: suitable

检测方法

fluorometric (Luminex xMAP)

运输

wet ice

一般描述

Maintenance of physiological balance in the body is attributed in part to normal kidney function. Altered kidney function due to injury, drug toxicity or kidney failure may be life threatening. Toxicity is the leading cause of drug failure, so research is expanding in search of more sensitive, rapid methods to determine organ-specific damage as quickly as possible. Traditionally, blood urea nitrogen (BUN) and serum creatinine tests have been used to determine drug-induced damage to the kidney. These tests only detect kidney damage after it begins and do not allow for the elucidation of where in the kidney the damage has occurred. Specificity and earlier detection of kidney injury is vital, and this area of research is expanding in search of more sensitive, rapid methods for determining the specific area of damage in kidney.

The MILLIPLEX^® portfolio provides valuable research assays to investigate multiple biomarkers of kidney injury in human urine samples using the Luminex^® xMAP^® instrument platform. The analytes available for this multiplex kit are: α-1-Microglobulin, Albumin, Clusterin, Cystatin C, EGF, Lipocalin-2/NGAL, and Osteopontin (OPN).

Panel Type: Toxicity

应用

Analytes: α-1-Microglobulin, Albumin, Clusterin, Cystatin C, EGF, Lipocalin-2/NGAL, Osteopontin (OPN)
Recommended Sample type: Urine
Recommended Sample dilution: 1:100 in kit Assay Buffer. Customers need to determine the optimal dilution factor for their samples. Our recommendations are based on urine samples from normal subjects.
Assay Run Time: Overnight
Research Category: Toxicity

生化/生理作用

Cross Reactivty
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes within a panel.

特点和优势

Design your multiplex kit by choosing available analytes within this panel.

其他说明

Sensitivity: Please see kit protocol for individual assay sensitivities.

法律信息

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.