产品名称
MILLIPLEX® Human Kidney Injury Panel,
species reactivity
human
Quality Level
description
Configurable Human Kidney Toxicity 6-plex Panel 5
packaging
pkg of 1 ea
manufacturer/tradename
Milliplex®
assay range
accuracy: 62-90%, intra-assay cv: <10, sensitivity: 0.05-0.56 ng/mL
(MinDC+2SD), standard curve range: 0.05-50 ng/mL
(Lipocalin-2/NGAL), standard curve range: 0.05-50 ng/mL
(Uromodulin), standard curve range: 0.10-100 ng/mL
(TIMP-1), standard curve range: 0.20-200 ng/mL
(Osteoactivin), standard curve range: 0.24-250 ng/mL
(α-1-Microglobulin), standard curve range: 0.49-500 ng/mL
(Collagen IV)
technique(s)
multiplexing: suitable
input
serum
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
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General description
Application
Analytes included: α-1-Microglobulin, Collagen IV, Lipocalin-2/NGAL, Osteoactivin, TIMP-1, Uromodulin
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
- Multiplex Capability: Simultaneous quantification of up to 6 kidney injury biomarkers in a single sample
- Magnetic Bead-Based Technology: Enables high-throughput and precise analyte detection using Luminex® xMAP® technology
- Validated for Human Serum and Plasma: Optimized for use with clinically relevant sample types
- Wide Dynamic Range: Detects low to high concentrations of biomarkers with excellent sensitivity
- Comprehensive Biomarker Coverage: Includes α-1-Microglobulin, Collagen IV, Lipocalin-2/NGAL, Osteoactivin, TIMP-1, and Uromodulin
- Flexible Format: Available in a 96-well plate configuration for streamlined workflow integration
- Efficient Sample Use: Requires minimal sample volume while delivering rich data across multiple biomarkers
- Accelerated Research: Ideal for translational studies, drug safety assessments, and nephrotoxicity profiling
- Improved Data Quality: High reproducibility and precision reduce variability and enhance confidence in results
- Time and Cost Savings: Reduces assay time and reagent consumption compared to singleplex methods
Legal Information
Disclaimer
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
target_organs
Respiratory Tract
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
法规信息
相关内容
Multiplex toxicity assays enable researchers to simultaneously measure multiple toxicity biomarkers of various organs to gain a better understanding of toxicity. Explore how MILLIPLEX® multiplex toxicity assays are advancing research on liver injury, kidney toxicity, genotoxicity, and more.
Novel kidney toxicity biomarkers expand options for acute nephrotoxicity detection. Multiplex assays measure multiple renal damage biomarkers in small sample volumes, minimizing time and costs. See how MILLIPLEX® multiplex kidney toxicity assays detected vancomycin-induced subacute nephrotoxicity in rat models.
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