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Merck
CN

HKI6MAG-99K

MILLIPLEX® Human Kidney Injury Panel

Configurable Human Kidney Toxicity 4-plex Panel 6

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UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

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产品名称

MILLIPLEX® Human Kidney Injury Panel, Configurable Human Kidney Toxicity 4-plex Panel 6

species reactivity

human

Quality Level

200

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

accuracy: 103-133%
intra-assay cv: <10
sensitivity: 0.10-3.42 ng/mL
(MinDC+2SD)
standard curve range: 0.05-50 ng/mL
(β-2-Microglobulin (β2M))
standard curve range: 0.10-100 ng/mL
(RBP4)
standard curve range: 0.59-600 ng/mL
(Cystatin C)
standard curve range: 2.93-3,000 ng/mL
(Clusterin)

technique(s)

multiplexing: suitable

input

serum

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

相关类别

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 4 analytes in human serum or plasma samples.Analytes included: β-2-Microglobulin, Clusterin, Cystatin C, Retinol Binding Protein 4 (RBP4)Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Disclaimer

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Features:• Multiplex capability for simultaneous detection of 4 analytes• Magnetic bead-based format compatible with Luminex® xMAP® technology• Verified biomarkers: β-2-Microglobulin, Clusterin, Cystatin C, Retinol Binding Protein 4 (RBP4)• Optimized for use with human serum and plasma samples• Includes all necessary reagents, standards, and controls• Designed for overnight incubation for enhanced sensitivityBenefits:• Conserves sample volume and reduces assay time• Improves reproducibility and throughput with magnetic bead handling• Enables comprehensive profiling of kidney injury biomarkers• Supports toxicology and nephrology research applications• Streamlines workflow with ready-to-use components

General description

Beta-2 Microglobulin, Clusterin, Cystatin C, Lipocalin-2/NGAL, Osteopontin, TFF-3, and Uromodulin are biomarkers associated with kidney injury, inflammation, and tubular function. These analytes help detect early signs of renal damage, immune activation, and epithelial stress, offering valuable insights into both acute and chronic kidney conditions. Their combined measurement supports sensitive and specific evaluation of renal health.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

法规信息

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R Mateo-Gallego et al.
Nutrition, metabolism, and cardiovascular diseases : NMCD, 28(2), 133-142 (2018-01-14)
High-protein (HP) diets have shown benefits in cardiometabolic markers such as insulin or triglycerides but the responsible mechanisms are not known. We aimed to assess the effect of three energy-restricted diets with different protein contents (20%, 27%, and 35%; ∼80%

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