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Merck
CN

HNS1MAG-95K

Millipore

MILLIPLEX® Human Neuroscience Magnetic Bead Panel 1 - Neuroscience Multiplex Assay

allows quantitative multiplex detection of multiple analytes simultaneously

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UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.47

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质量水平

200

种属反应性

human

制造商/商品名称

Milliplex®

assay range

accuracy: 107%
(DJ1)
accuracy: 108%
(a-Synuclein)
accuracy: 123%
(TG2)
standard curve range: 12-50,000 pg/mL
(GFAP)
standard curve range: 15-60,000 pg/mL
(NSE)
standard curve range: 20-80,000 pg/mL
(UCHL1)
standard curve range: 244-1,000,000 pg/mL
(alpha-synuclein)
standard curve range: 61-250,000 pg/mL
(DJ1)
standard curve range: 61-250,000 pg/mL
(TG2)

技术

multiplexing: suitable

检测方法

fluorometric (Luminex xMAP)

运输

ambient

相关类别

一般描述

Neurological dysfunction may be initiated by a broad spectrum of diseases, as well as physical injury to the brain or spinal cord. Numerous potential biomarkers of neurological dysfunction have been identified. The ability to perform multiplex analysis of these biomarkers offers a valuable research tool to better understand this area of neuroscience.

MILLIPLEX® Human Neuroscience Bead Panel 1 is a 6-plex kit to be used for the simultaneous quantification of any or all of the following analytes in cerebrospinal fluid (CSF) samples: α-Synuclein, DJ1/PARK7, Glial fibrillary acidic protein (GFAP), Neuron specific enolase (NSE), Transglutaminase 2 (TGM2), and Ubiquitin carboxyl-terminal esterase L1 (UCHL1/PARK5).

Panel Type: Neuroscience

应用

  • Analytes: GFAP, NSE, α-Synuclein, PARK5, Transglutaminase 2 (TGM2)
  • Recommended Sample type: CSF
  • Recommended Sample dilution: Neat
  • Assay Run Time: Overnight or one day
  • Research Category: Neuroscience

生化/生理作用

Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

特点和优势

Design your multiplex kit by choosing available analytes within this panel.

包装

Everything you need in a single kit.

制备说明

Recommended storage for kit components is 2 - 8°C.

其他说明

Sensitivity: See protocol for sensitivities of individual analytes

法律信息

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Daniela Diaz-Lucena et al.
Journal of neurology, 267(9), 2567-2581 (2020-05-07)
Differential diagnosis of neurodegenerative dementia is currently supported by biomarkers including cerebrospinal fluid (CSF) tests. Among them, CSF total-tau (t-tau), phosphorylated tau (p-tau) and β-amyloid42 (Aβ42) are considered core biomarkers of neurodegeneration. In the present work, we hypothesize that simultaneous
Martin Trapecar et al.
Science advances, 7(5) (2021-01-31)
Slow progress in the fight against neurodegenerative diseases (NDs) motivates an urgent need for highly controlled in vitro systems to investigate organ-organ- and organ-immune-specific interactions relevant for disease pathophysiology. Of particular interest is the gut/microbiome-liver-brain axis for parsing out how

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