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Merck
CN

M04S-03-5PK

CellASIC ONIX切换板哺乳动物细胞（4腔室）

The M04 switching plates enable continuous perfusion culture for live cell analysis. Laminar flow provides rapid & uniform solution exchange for maximum cell health. The glass coverslide bottom surface ensures the highest resolution optical viewing.

别名:

CellASIC ONIX板, ONIX切换板, 哺乳动物细胞培养板

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UNSPSC Code:
41104923
NACRES:
NB.22
eCl@ss:
32011202
Material:
PMMA , glass , polycarbonate , polydimethylsiloxane (PDMS)
Manufacturer/tradename:
CellASIC® ONIX

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material

PMMA , glass , polycarbonate , polydimethylsiloxane (PDMS)

manufacturer/tradename

CellASIC® ONIX

W × L × H

85.48 mm × 127.76 mm × 14.35 mm

compatibility

for use with cells sized up to 50.0 μm

shipped in

ambient

相关类别

General description

CellASIC® ONIX 哺乳细胞切换板（4 腔室）可实现连续灌注培养以进行活细胞分析。层流为最大限度细胞健康提供快速均匀的溶液交换。玻璃盖玻片底面可确保最高分辨率的光学观察。

Application

CellASIC® ONIX 哺乳细胞切换板（4 腔室）已用于：
  • 活细胞成像以研究phi-particle对动力蛋白的自动抑制以及动力蛋白激活蛋白活化动力蛋白的贡献。
  • 通过荧光显微镜技术进行fcSAgA结合和免疫球蛋白M表面聚集的活细胞成像
  • 多重表皮生长因子（EGF）脉冲实验
CellASIC® ONIX 转换板适用于：
  • 粘附细胞的延时分析（time-lapse analysis）
  • 长期连续灌注实验（通常3天）
  • 溶液交换实验（诱导、抑制、给药）
  • 培养室内活细胞的自动免疫染色和按需固定
  • 平行比较四种不同细胞类型或暴露条件（培养基成分）、温度和气体气氛控制（温度变化、缺氧条件等）

Features and Benefits

  • 兼容CellASIC® ONIX2 微流体系统和ONIX2 Manifolds
  • 可以用溶液切换进行基于灌注的长期活细胞分析
  • 板为2D和3D细胞培养物提供受控的动态微环境。

Legal Information

CELLASIC is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

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Brittany L Hartwell et al.
Biomacromolecules, 18(6), 1893-1907 (2017-05-06)
A pressing need exists for antigen-specific immunotherapies (ASIT) that induce selective tolerance in autoimmune disease while avoiding deleterious global immunosuppression. Multivalent soluble antigen arrays (SAgAPLP:LABL), consisting of a hyaluronic acid (HA) linear polymer backbone cografted with multiple copies of autoantigen
Kai Zhang et al.
Cell, 169(7), 1303-1314 (2017-06-13)
Cytoplasmic dynein-1 binds dynactin and cargo adaptor proteins to form a transport machine capable of long-distance processive movement along microtubules. However, it is unclear why dynein-1 moves poorly on its own or how it is activated by dynactin. Here, we
Angel Stanoev et al.
Cell systems, 7(3), 295-309 (2018-08-27)
The proto-oncogenic epidermal growth factor receptor (EGFR) is a tyrosine kinase whose sensitivity to growth factors and signal duration determines cellular behavior. We resolve how EGFR's response to epidermal growth factor (EGF) originates from dynamically established recursive interactions with spatially

商品

Dynamic Live Cell Imaging of Caspase Mediated Apoptosis and Cellular Hypoxia in Lymphocytes and Cancer Cells Using the CellASIC® ONIX2 Microfluidic Platform

Application note on how the CellASIC® ONIX2 microfluidic system can be used to analyze caspase-3 mediated apoptosis/cell death and cellular hypoxia in live immune and cancer cell lines.

相关内容

CellASIC® ONIX2 Microfluidic System

Convert your microscope to a live cell imaging system – the CellASIC® ONIX2 system allows precise manipulation of the cell culture environment for dynamic live cell imaging and analysis using mammalian, yeast, and bacterial cells.

進化した顕微鏡用ライブセルイメージング環境制御ツールCellASIC ONIX2 微小流体システム
Live cell imaging of yeast with the CellASIC®platform reveals effect of the extracellular milieu
CellASIC®ONIX Microfluidic System

Design dynamic experiments with the CellASIC™ ONIX Microfluidic Platform. With microfluidic precision, you can push the boundaries of your cell biology experiments in an in vivo-like environment. This new perfusion-based system enables you to program automated changes to culture conditions while maintaining optical access to cells through your microscope. You can even track individual cell responses over time by using a time-lapse-enabled microscope for truly dynamic cellular analysis.

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