产品名称
Anti-CCT-beta Antibody, clone F39 P7 F11, clone F39 P7 F11, Chemicon®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
F39 P7 F11, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
western blot: suitable
isotype
IgG2aκ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PCYT1B(9468)
Analysis Note
Control
Tested on Hela cell lysate
Tested on Hela cell lysate
Application
Research Category
Protein Trafficking
Protein Trafficking
Research Sub Category
Chaperones
Chaperones
This Anti-CCT-beta Antibody, clone F39 P7 F11 is validated for use in WB for the detection of CCT-beta.
Western Blot Analysis: 0.1 - 0.5 ug/mL of this antibody detects a 60 kDa band of CCT-beta in HeLa cell lysate.
Optimal antibody dilution must be determined by end-user.
Optimal antibody dilution must be determined by end-user.
Biochem/physiol Actions
CCT-beta
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
60 kDa
This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the gene described in this record have been observed but have not been thoroughly characterized.
Immunogen
Synthetic Peptide corresponding to the C-Terminus of Human CCT-beta
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Format: Purified
Protein A purified
Purified mouse monoclonal IgG2aκ in buffer containing PBS and 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
未找到合适的产品？
试试我们的产品选型工具.
存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Heba Ghozlan et al.
Frontiers in oncology, 11, 663877-663877 (2021-05-18)
Uncontrolled proliferation as a result of dysregulated cell cycling is one of the hallmarks of cancer. Therapeutically targeting pathways that control the cell cycle would improve patient outcomes. However, the development of drug resistance and a limited number of inhibitors
Anne E Showalter et al.
Scientific reports, 10(1), 798-798 (2020-01-23)
Chaperonin-containing TCP-1 (CCT or TRiC) is a multi-subunit complex that folds many of the proteins essential for cancer development. CCT is expressed in diverse cancers and could be an ideal therapeutic target if not for the fact that the complex
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持