MAB10404
Anti-Ghrelin Antibody, clone 1ML-1D7
ascites fluid, clone 1ML-1D7, from mouse
别名:
ghrelin/obestatin prepropeptide1, ghrelin/obestatin2, ghrelin, growth hormone secretagogue receptor ligand1, obestatin1, ghrelin/obestatin preprohormone, Motilin-related peptide2, ghrelin1, M46 protein3, Growth hormone secretagogue
产品名称
Anti-Ghrelin Antibody, clone 1ML-1D7, ascites fluid, clone 1ML-1D7, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
1ML-1D7, monoclonal
species reactivity
mouse, human
technique(s)
immunocytochemistry: suitable
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GHRL(51738)
Analysis Note
Control
Mouse stomach tissue lysate
Mouse stomach tissue lysate
Evaluated by Western Blot in mouse stomach tissue lysate.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected Ghrelin in 10 µg of mouse stomach tissue lysate.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected Ghrelin in 10 µg of mouse stomach tissue lysate.
Application
Detect Ghrelin using this Anti-Ghrelin Antibody, clone 1ML-1D7 validated for use in WB & IC.
Immunocytochemistry Analysis: A 1:500 dilution from a previous lot detected Ghrelin in A431 cells.
Biochem/physiol Actions
This antibody recognizes Ghrelin at the N-terminus.
General description
13 kDa calculated and observed
Ghrelin is a 28 amino acids peptide with an essential n-octonayl modification at Serine 3. This peptide hormone is known as an endogenous ligand for the growth hormone secretagogue receptor and shares sequence similarity with the peptide hormone Motilin. Ghrelin displays pleotropic actions including growth hormone secretion, feeding behaviour and gastrointestinal motility. It is predominantly produced by enteroendocrine cells from the gastrointestinal tract, but has been shown to play a significant role in neurotrophy, particularly in the hippocampus, and appears to be essential for cognitive adaptation to changing environments and the process of learning.
Immunogen
Linear Peptide corresponding to the N-terminus of human Ghrelin.
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存储类别
10 - Combustible liquids
wgk
WGK 1
Cindy Y Kok et al.
Gene therapy, 31(3-4), 165-174 (2024-01-05)
Ghrelin is commonly known as the 'hunger hormone' due to its role in stimulating food intake in humans. However, the roles of ghrelin extend beyond regulating hunger. Our aim was to investigate the ability of ghrelin to protect against hydrogen
Bing Li et al.
International journal of clinical and experimental pathology, 8(12), 15993-15999 (2016-02-18)
Maternal stress exerts long-lasting postnatal growth on offspring, which persist into adulthood. However, the effect of maternal stress on appetizing system has not been widely reported. In this study, we found that maternal immobilization stress (IS) during lactation resulted in
Histopathologic and immunohistochemical sequelae of bariatric embolization in a porcine model.
Paxton, BE; Alley, CL; Crow, JH; Burchette, J; Weiss, CR; Kraitchman, DL; Arepally, A; Kim, CY
Journal of Vascular and Interventional Radiology : Jvir null
Wei Wei et al.
Cell metabolism, 19(6), 927-940 (2014-05-06)
Orexin neuropeptides promote arousal, appetite, reward, and energy expenditure. However, whether orexin affects bone mass accrual is unknown. Here, we show that orexin functions centrally through orexin receptor 2 (OX2R) in the brain to enhance bone formation. OX2R null mice
Tiziana Napolitano et al.
Cells, 10(11) (2021-11-28)
Background: Although several approaches have revealed much about individual factors that regulate pancreatic development, we have yet to fully understand their complicated interplay during pancreas morphogenesis. Gfi1 is transcription factor specifically expressed in pancreatic acinar cells, whose role in pancreas
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