MAB1155
抗干扰素-α/β受体链 2 抗体，克隆 MMHAR-2
clone MMHAR-2, Chemicon®, from mouse
别名:
CD118
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
MMHAR-2, monoclonal
Application:
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
immunohistochemistry
immunoprecipitation (IP)
Species reactivity:
human
Citations:
25
Technique(s):
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
Uniprot accession no.:
产品名称
抗干扰素-α/β受体链 2 抗体，克隆 MMHAR-2, clone MMHAR-2, Chemicon®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
MMHAR-2, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
isotype
IgG2a
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... IFNA1(3439)
Application
抗干扰素-α/β 受体链 2 抗体, 克隆 MMHAR-2 是一种抗干扰素-α/β 受体链 2 抗体，用于 FC、IP、IH。
生物学研究
免疫沉淀：（1-5 μg/mL）
免疫组织化学：（1μg/mL）
流式细胞术：（1 μg/10 mL - 用 50% 人 AB 血清封闭细胞）
最佳工作稀释度必须由最终用户确定。
免疫沉淀：（1-5 μg/mL）
免疫组织化学：（1μg/mL）
流式细胞术：（1 μg/10 mL - 用 50% 人 AB 血清封闭细胞）
最佳工作稀释度必须由最终用户确定。
研究子类别
细胞因子&细胞因子受体
细胞因子&细胞因子受体
研究类别
炎症 & 免疫学
炎症 & 免疫学
Biochem/physiol Actions
与人干扰素 α/β 受体链 2 (CD118) 发生反应。 抗体中和人干扰素α受体，与细胞外结构域相互作用，以高亲和力与人干扰素α受体结合，并阻断I型干扰素的生物学作用。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Immunogen
人干扰素α/β受体链2
Other Notes
浓度：请参考批次特异性浓缩物的检验报告。
Physical form
形式：纯化
纯化的免疫球蛋白。 含有 0.1% 牛血清白蛋白 (BSA) 的 PBS 液体。
Preparation Note
在-20°C 或以下冷冻保存，以保留全部活性，最长可保存 12 个月。解冻时，应将试管中的内容物分装在单独的试管中，以便将冷冻和解冻保持在最低限度。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Ting Zhang et al.
Hepatology (Baltimore, Md.), 42(4), 819-827 (2005-09-22)
The chronicity of hepatitis C virus (HCV) infection raises the question of how HCV is able to persist in hepatic cells. We show that human primary hepatocytes and human hepatic cell lines (Huh7 and HepG2) spontaneously produce interferon (IFN)-alpha that
Chlamydia trachomatis-infected epithelial cells and fibroblasts retain the ability to express surface-presented major histocompatibility complex class I molecules.
Kagebein, D; Gutjahr, M; Gro?e, C; Vogel, AB; Rodel, J; Knittler, MR
Infection and Immunity null
Aura Muntasell et al.
Frontiers in immunology, 4, 40-40 (2013-02-27)
Natural killer (NK) cells play an important role in the defense against viral infections. Activation of resting NK cells is tightly controlled by the balance of surface inhibitory and activating receptors and aided by cytokines released by accessory cells along
G Pollara et al.
Scandinavian journal of immunology, 63(3), 151-154 (2006-02-28)
The central role of dendritic cells (DC) in the initiation of immune responses requires these cells to be able to determine the degree of danger in their microenvironment. Abrogating the activity of type I interferon (IFN) secreted after lipopolysaccharide (LPS)
Joshua Ogony et al.
Breast cancer research : BCR, 18(1), 25-25 (2016-02-22)
Inflammatory breast cancer (IBC) is a very aggressive and lethal subtype of breast cancer that accounts for about 4 % of all breast cancers diagnosed in the United States. Despite the efforts of several investigators to identify the molecular factors driving
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