biological source
mouse
Quality Segment
conjugate
ALEXA FLUOR™ 488
antibody form
purified antibody
antibody product type
primary antibodies
clone
513, monoclonal
species reactivity
rat, mouse
species reactivity (predicted by homology)
chicken (based on 100% sequence homology), human (based on 100% sequence homology), frog (based on 100% sequence homology), bovine (based on 100% sequence homology)
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... MAG(4099)
General description
69 kDa calculated
Myelin-associated glycoprotein (MAG), a member of the immunoglobulin superfamily, is a membrane glycoprotein of 100 kDa, and is thought to be involved in the process of myelination. Axonal regeneration in the adult central nervous system (CNS) is limited by two proteins in myelin, Nogo and MAG. MAG has been implicated in the inhibition of nerve regeneration in the CNS.
Immunogen
L2 epitope carrying glycoprotein extract of 1-2 day old chicken brain
Application
Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected MAG in rat E18 primary cortex cells.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Neuroscience
Developmental Neuroscience
This Anti-MAG Antibody, clone 513, Alexa Fluor 488 Conjugate is validated for use in IC, IH for the detection of MAG.
Physical form
Protein A purified
Purified mouse monoclonal IgG1 conjugated to Alexa Fluor™ 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Preparation Note
Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Analysis Note
Control
Adult mouse brain tissue
Adult mouse brain tissue
Evaluated by Immunohistochemistry in adult mouse brain tissue.
Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected MAG in adult mouse brain tissue.
Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected MAG in adult mouse brain tissue.
Legal Information
ALEXA FLUOR is a trademark of Life Technologies
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2