CN
生物来源
mouse
质量水平
抗体形式
purified antibody
antibody product type
primary antibodies
克隆
18C7.2, monoclonal
纯化方式
using Protein A
species reactivity
monkey
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgG1
NCBI登记号
UniProt登记号
运输
wet ice
target post-translational modification
unmodified
Gene Information
rhesus monkey ... Chrm4(574195)
特异性
m4 muscarinic acetylcholine receptor. No reactivity with the other subtypes.
免疫原
m4 receptor i3 loop (human), fused to GST
应用
Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 18C7.2 detects level of Muscarinic Acetylcholine Receptor m4 & has been published & validated for use in IH, IP & WB.
Immunohistochemistry (monkey)
Western blot (transfected CHO cell lines)
Immunoprecipitation (rat and monkey)
Optimal working dilutions must be determined by the end user.
Western blot (transfected CHO cell lines)
Immunoprecipitation (rat and monkey)
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
外形
Liquid in 0.02M Phosphate buffer, 0.25 M NaCl with 0.1% sodium azide.
储存及稳定性
Maintain at 2-8°C in undiluted aliquots for up to 6 months.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
分析证书(COA)
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示例
T1503
货号
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25G
包装规格/数量
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1000309185
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G Q Li et al.
Neuroscience, 146(1), 384-402 (2007-03-30)
Muscarinic acetylcholine receptors (mAChRs) are widely expressed in the CNS and peripheral nervous system and play an important role in modulating the cell activity and function. We have shown that the cholinergic agonist carbachol reduces the pigeon's inwardly rectifying potassium
Deborah Bauer et al.
Schizophrenia research, 117(1), 92-98 (2009-09-01)
The excitatory amino acid transporters (EAATs) are a family of molecules that are essential for regulation of synaptic glutamate levels. The EAATs may also be regulated by N-glycosylation, a posttranslational modification that is critical for many cellular functions including localization
Christianne E Strang et al.
Investigative ophthalmology & visual science, 51(5), 2778-2789 (2010-01-01)
The activation and blockade of muscarinic acetylcholine receptors (mAChRs) affects retinal ganglion cell light responses and firing rates. This study was undertaken to identify the full complement of mAChRs expressed in the rabbit retina and to assess mAChR distribution and
Judith Molina et al.
Diabetes, 63(8), 2714-2726 (2014-03-25)
Acetylcholine regulates hormone secretion from the pancreatic islet and is thus crucial for glucose homeostasis. Little is known, however, about acetylcholine (cholinergic) signaling in the human islet. We recently reported that in the human islet, acetylcholine is primarily a paracrine
Jivan Khlghatyan et al.
Cerebral cortex (New York, N.Y. : 1991), 29(9), 3813-3827 (2018-10-09)
Cortical D2 dopamine receptor (Drd2) have mostly been examined in the context of cognitive function regulation and neurotransmission modulation of medial prefrontal cortex by principal neurons and parvalbumin positive, fast-spiking, interneurons in schizophrenia. Early studies suggested the presence of D2
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