产品名称
抗角蛋白上皮抗体（克隆AE3）, clone AE3, Chemicon®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
clone
AE3, monoclonal
species reactivity
rat, chicken, rabbit, mouse, human, monkey, bovine
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable (paraffin)
western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
相关类别
Analysis Note
对照
阳性对照：MCF-7、RT112和A431细胞系。：
阳性对照：MCF-7、RT112和A431细胞系。：
Application
抗角蛋白上皮抗体（克隆AE3）是针对角蛋白上皮的抗体，可用于 WB、IH（P）。
未固定冷冻切片或福尔马林固定、石蜡包埋组织切片的免疫组织化学：对于石蜡包埋切片，强烈建议进行抗体修复（HEIR 或胰蛋白酶处理）。
蛋白质印迹：克隆AE3 识别碱性亚家族（basic subfamily）65 至 67、64、59、58、56和52 kDa人细胞角蛋白。
最佳工作稀释度必须由最终用户进行确定。
蛋白质印迹：克隆AE3 识别碱性亚家族（basic subfamily）65 至 67、64、59、58、56和52 kDa人细胞角蛋白。
最佳工作稀释度必须由最终用户进行确定。
研究子类别
细胞角蛋白
细胞角蛋白
研究类别
细胞结构
细胞结构
Biochem/physiol Actions
识别大多数碱性（II型）角蛋白，即HMW细胞角蛋白。它反应性广泛，并可使大多数上皮细胞及其肿瘤阳性染色。AE3 与表皮的所有层（基底层及以上层）反应。该抗体是区分癌和非上皮肿瘤的良好标志物。 它被用于研究表皮角蛋白的免疫定位、角蛋白的组织分布、各种表皮疾病、口腔粘膜和其它上皮的发育。 AE3 和AE1（货号MAB1612） 广泛用于区分癌和非癌组织。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Immunogen
人表皮细胞
Other Notes
替代：04-588
浓度：请参考批次特异性浓缩物的检验报告。
Physical form
形式：纯化
溶于PBS中的液体。含0.1%叠氮化钠。
Preparation Note
自接收之日起，以未稀释的等分试样在2-8°C下保存长达6个月。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Repr. 1B
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Immortal tumor cell lines are an important model system for cancer research, however, misidentification and cross-contamination of cell lines are a common problem. Seven chordoma cell lines are reported in the literature, but none has been characterized in detail. We
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