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MAB1957

Sigma-Aldrich

Anti-Integrin beta 3 (ITGB3/CD61) Antibody

CHEMICON®, mouse monoclonal, 25E11

别名:

CD61

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100 UNITS
CN¥1,187.62
500 UNITS
CN¥4,474.91
500 UNITS
CN¥4,742.62

CN¥1,187.62

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100 UNITS
CN¥1,187.62
500 UNITS
CN¥4,474.91
500 UNITS
CN¥4,742.62

About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

CN¥1,187.62

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Product Name

Anti-Integrin β3 Antibody, clone 25E11, clone 25E11, Chemicon®, from mouse

生物来源

mouse

质量水平

100

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

25E11, monoclonal

种属反应性

human

制造商/商品名称

Chemicon®

技术

flow cytometry: suitable
immunocytochemistry: suitable
immunoprecipitation (IP): suitable

同位素/亚型

IgM

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DNA Ligase from T4-infected Escherichia coli buffered aqueous glycerol solution

D2886

DNA Ligase from T4-infected Escherichia coli

technique(s)

activity assay: suitable

technique(s)

-

technique(s)

molecular cloning: suitable

technique(s)

-

biological source

Escherichia coli (NM 989)

biological source

-

biological source

-

biological source

-

specific activity

~3000 units/mg protein

specific activity

-

specific activity

-

specific activity

4,000 U/mL

recombinant

expressed in E. coli

recombinant

-

recombinant

-

recombinant

-

form

solution

form

-

form

liquid

form

buffered aqueous glycerol solution

storage temp.

−20°C

storage temp.

-

storage temp.

−20°C

storage temp.

−20°C

特异性

Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). The protein detectable is a complex of CD41 and CD61. The apparent molecular weight of the GPIIIa by SDS-PAGE is 105 kDa reduced and 90 kDa unreduced. Ligands are fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding. The monocytoid cell line U937 is highly positive.

(original paper claimed IgG2ak)

免疫原

Normal blood mononuclear cells activated by mixed lymphocyte reaction and cultured for 10 days in medium containing IL-2.

应用

Immunoprecipitation

Immunocytochemistry (acetone fixation required)

Flow cytometry

Inhibits platelet aggregation, 10 μg/mL

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
Integrins
This Anti-Integrin β3 Antibody, clone 25E11 is validated for use in FC, IP, IC, FUNC for the detection of Integrin β3.

联系

Replaces: 04-1060

外形

Format: Purified
In buffer of 0.02M phosphate, 0.25M sodium chloride, pH 7.6, 0.1% sodium azide.

储存及稳定性

Maintain between 2 and 8°C.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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