biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
P4H9, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
isotype
IgG3
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ITGB2(3689)
Application
Detect Integrin β2 using this Anti-Integrin β2 Antibody, clone P4H9 validated for use in IH.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
Suitable for use in immunofluorescence at 1:1000.
Also suitable for aggregation inhibition assays using hematopoeitic cells or EBV-transformed B lymphocytes.
For extensive dilution, protein-containing or other stabilizing medium should be used. Final working dilutions must be determined by end user.
Also suitable for aggregation inhibition assays using hematopoeitic cells or EBV-transformed B lymphocytes.
For extensive dilution, protein-containing or other stabilizing medium should be used. Final working dilutions must be determined by end user.
Biochem/physiol Actions
beta2 integrin on hematopoeitic cells. Not present on platelets, endothelial cells, epithelial cells or fibroblasts.
Physical form
Format: Purified
Non-sterile buffer of 0.02M phosphate, 0.25M Sodium Chloride, pH 7.6,
0.1% sodium azide.
0.1% sodium azide.
Preparation Note
Maintain between 2 and 8°C.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Elzbieta Pluskota et al.
The Journal of biological chemistry, 279(17), 18063-18072 (2004-02-11)
Plasmin, the pivotal thrombolytic enzyme, is generated on the surface of many cell types, where urokinase receptor (uPAR)-bound urokinase (uPA) activates cell-bound plasminogen (Plg). It has been reported that neutrophils mediate endogenous thrombolysis involving a uPA-dependent mechanism, and we previously
Elzbieta Pluskota et al.
Blood, 101(4), 1582-1590 (2002-10-24)
Previous studies demonstrated that integrin alpha(M)beta(2) (CD11b/18, Mac-1) forms a physical complex with the urokinase-type plasminogen activator receptor (uPAR/CD87) on leukocytes. In this study, we used human peripheral blood neutrophils and transfected cells expressing alpha(M)beta(2), uPAR, or both receptors to
I N Gavrilovskaya et al.
Journal of virology, 73(5), 3951-3959 (1999-04-10)
Hantaviruses replicate primarily in the vascular endothelium and cause two human diseases, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). In this report, we demonstrate that the cellular entry of HFRS-associated hantaviruses is facilitated by specific integrins
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MAB1962 | 04053252615931 |