MAB2035
Anti-Aggrecan Antibody
CHEMICON®, mouse monoclonal, MK-302
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关于此项目
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
MK-302, monoclonal
Species reactivity:
canine, sheep, rat, rabbit, mouse, bovine, human
Application:
ELISA, RIA, WB
Citations:
26
产品名称
抗硫酸软骨素6抗体，克隆MK-302, ascites fluid, clone MK-302, Chemicon®
biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
MK-302, monoclonal
species reactivity
canine, sheep, rat, rabbit, mouse, bovine, human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, radioimmunoassay: suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... ACAN(176)
Immunogen
软骨素酶ABC消化的成年人聚集蛋白聚糖。
Application
ELISA在1：100-1：5,000
RIA在1：100-1：200。
抗体反应性需要在抗体反应之前进行软骨素酶ABC消化。{0.5 U/ml 100mM Tris-HCL，室温下30分钟}核心蛋白的剧烈蛋白水解消化（例如用木瓜蛋白酶或链霉蛋白酶）显著降低了抗体反应性。
最佳工作稀释度必须由最终用户进行确定。
RIA在1：100-1：200。
抗体反应性需要在抗体反应之前进行软骨素酶ABC消化。{0.5 U/ml 100mM Tris-HCL，室温下30分钟}核心蛋白的剧烈蛋白水解消化（例如用木瓜蛋白酶或链霉蛋白酶）显著降低了抗体反应性。
最佳工作稀释度必须由最终用户进行确定。
抗硫酸软骨素6抗体（克隆MK-302）是一种抗硫酸软骨素6抗体，用于ELISA、RIA &WB。
Biochem/physiol Actions
软骨素酶（ABC或AC）或睾丸透明质酸酶消化后可与多种软骨蛋白聚糖反应。 天然蛋白聚糖不与MAB2035反应。 硫酸软骨素6的二糖成功抑制了与表位结合的抗体。 识别不同物种的高密度软骨蛋白聚糖的硫酸软骨素6（优先成簇）。 与硫酸皮肤素、硫酸角质素或硫酸软骨素4无交叉反应。
Physical form
腹水液；无防腐剂。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Qijing Wu et al.
Cancer immunology research, 10(2), 182-199 (2021-12-23)
Metastatic microsatellite-stable (MSS) colorectal cancer rarely responds to immune checkpoint inhibitors (ICI). Metabolism heterogeneity in the tumor microenvironment (TME) presents obstacles to antitumor immune response. Combining transcriptome (The Cancer Genome Atlas MSS colorectal cancer, n = 383) and digital pathology
G D Nicodemus et al.
Journal of biomechanics, 41(7), 1528-1536 (2008-04-18)
Crosslinked poly(ethylene glycol) (PEG) hydrogels are attractive scaffolds for cartilage tissue engineering because of their ability to mimic the aqueous environment and mechanical properties of native cartilage. In this study, hydrogel crosslinking density was varied to study the influence of
Rowena C Cua et al.
Glia, 61(6), 972-984 (2013-04-05)
Acute trauma to the central nervous system (CNS) can result in permanent damage and loss of function related to the poor regeneration of injured axons. Injured axons encounter several barriers to regeneration, such as the glial scar at the injury
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MAB2035 | 04053252613104 |