MAB2056Z
Anti-Integrin α3 Antibody, clone ASC-1 (Azide Free)
clone ASC-1, Chemicon®, from mouse
别名:
CD49c
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
ASC-1, monoclonal
Application:
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
immunohistochemistry
immunoprecipitation (IP)
Species reactivity:
human
Citations:
3
Technique(s):
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
Uniprot accession no.:
产品名称
Anti-Integrin α3 Antibody, clone ASC-1 (Azide Free), clone ASC-1, Chemicon®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
ASC-1, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ITGA3(3675)
Application
Inhibition (Functional Activity): A previous lot of this antibody was shown to inhibit cell attachment by inhibiting SCC9 cell adhesion to human and EHS laminin, and laminin GD-2 peptide and potentiates the inhibition of SKOV-3 cell adhesion to EHS laminin by anti-integrin alpha 5 antibody GoH3. This antibody does not inhibit cell adhesion to fibronectin or collagen type IV.
Immunohistochemistry Analysis: A previous lot of this antibody was used on acetone-fixed frozen human epithelial tissues including tongue, foreskin and ovary. Not for use on formalin-fixed tissue.
Flow Cytometry Analysis: A previous lot of this antibody stains human squamous cell carcinoma (SCC9), ovarian carcinoma (SKOV-3) and umbilical vein endothelial cells (HUVEC).
Immunoprecipitation Analysis: A previous lot of this antibody precipitates PAGE bands of 130 kDa (reduced) or 116 kDa and 135 kDa (non-reduced) from surface-biotinylated SCC9 or SKOV-3 cells.
Immunohistochemistry Analysis: A previous lot of this antibody was used on acetone-fixed frozen human epithelial tissues including tongue, foreskin and ovary. Not for use on formalin-fixed tissue.
Flow Cytometry Analysis: A previous lot of this antibody stains human squamous cell carcinoma (SCC9), ovarian carcinoma (SKOV-3) and umbilical vein endothelial cells (HUVEC).
Immunoprecipitation Analysis: A previous lot of this antibody precipitates PAGE bands of 130 kDa (reduced) or 116 kDa and 135 kDa (non-reduced) from surface-biotinylated SCC9 or SKOV-3 cells.
Anti-Integrin α3 Antibody, clone ASC-1 (Azide Free) inhibits cell attachment & detects level of Integrin α3 & has been published & validated for use in FC, IP, IH, Inhibition Assays.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
Biochem/physiol Actions
Human alpha3 integrin (CD49c)
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
116 kDa
Immunogen
Human squamous cell carcinoma cells (SCC9)
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Format: Purified
Purified antibody in PBS without preservatives.
Preparation Note
Store at -20°C in undiluted aliquots.
Avoid repeated freeze-thaw cycles.
Avoid repeated freeze-thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Nick J I Hamilton et al.
The European respiratory journal, 55(6) (2020-05-24)
Current methods to replace damaged upper airway epithelium with exogenous cells are limited. Existing strategies use grafts that lack mucociliary function, leading to infection and the retention of secretions and keratin debris. Strategies that regenerate airway epithelium with mucociliary function
J E Kim et al.
The Journal of biological chemistry, 275(40), 30907-30915 (2000-07-25)
betaig-h3 is a transforming growth factor-beta-inducible cell adhesion molecule that has four characteristic homologous repeated domains. We made recombinant betaig-h3 proteins, which were highly active in mediating human corneal epithelial (HCE) cell adhesion and spreading. The 2nd and the 4th
Daniela I Staquicini et al.
Med (New York, N.Y.), 2(3), 321-342 (2021-04-20)
The extensive alveolar capillary network of the lungs is an attractive route for administration of several agents. One key functional attribute is the rapid onset of systemic action due to the absence of first-pass metabolism. Here we applied a combinatorial
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