MAB2078Z
Anti-Integrin α9β1 Antibody, clone Y9A2, azide free
clone Y9A2, Chemicon®, from mouse
别名:
MAB2078
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
Y9A2, monoclonal
Application:
FACS, IP
Citations:
19
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
Y9A2, monoclonal
species reactivity
human, guinea pig
should not react with
rat
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable, immunoprecipitation (IP): suitable
isotype
IgG1
suitability
not suitable for Western blot, not suitable for immunohistochemistry
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ITGA9(3680)
Immunogen
Murine L cells transfected with human alpha9.
Application
Detect Integrin α9β1 using this Anti-Integrin α9β1 Antibody, clone Y9A2, azide free validated for use in FC & IP.
Immunoprecipitation
FACS Analysis
Function blocking: 100% inhibition of alpha9beta1-mediated adhesion to the third fibronectin type III repeat in tenascin at <10 μg/mL.
Not effective for immunohistochemistry, immunocytochemistry or western blot.
Optimal working dilutions must be determined by end user.
FACS Analysis
Function blocking: 100% inhibition of alpha9beta1-mediated adhesion to the third fibronectin type III repeat in tenascin at <10 μg/mL.
Not effective for immunohistochemistry, immunocytochemistry or western blot.
Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
Biochem/physiol Actions
Reactive with human and guinea pig alpha9beta1.
Physical form
Format: Purified
Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with no preservatives.
Protein A purified
Preparation Note
Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Analysis Note
Control
Integrin alpha9beta1 positive tissues include basal keratinocytes, hepatocytes, muscle (smooth and skeletal), and airway epithelium.
Integrin alpha9beta1 positive tissues include basal keratinocytes, hepatocytes, muscle (smooth and skeletal), and airway epithelium.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Koichi Nishino et al.
Scientific reports, 11(1), 8406-8406 (2021-04-18)
Lymphangioleiomyomatosis (LAM) is a rare pulmonary disease characterised by the proliferation of smooth muscle-like cells (LAM cells), and an abundance of lymphatic vessels in LAM lesions. Studies reported that vascular endothelial growth factor-D (VEGF-D) secreted by LAM cells contributes to
Patrick M Lelliott et al.
ImmunoHorizons, 6(2), 170-183 (2022-02-24)
Anti-neutrophil cytoplasmic Ab (ANCA)-associated vasculitis (AAV) is a life-threatening condition characterized by improper activation of neutrophils and the release of neutrophil extracellular traps (NETs) in small vessels. This study aimed to explain the role of NETs in AAV pathogenesis by
Whitney M Longmate et al.
The Journal of cell biology, 216(5), 1473-1488 (2017-04-19)
Development of wound therapies is hindered by poor understanding of combinatorial integrin function in the epidermis. In this study, we generated mice with epidermis-specific deletion of α3β1, α9β1, or both integrins as well as keratinocyte lines expressing these integrin combinations.
Jochen Grassinger et al.
Blood, 114(1), 49-59 (2009-05-07)
Osteopontin (OPN), a multifunctional acidic glycoprotein, expressed by osteoblasts within the endosteal region of the bone marrow (BM) suppresses the proliferation of hemopoietic stem and progenitor cells and also regulates their lodgment within the BM after transplantation. Herein we demonstrate
A V Timoshenko et al.
British journal of cancer, 97(8), 1090-1098 (2007-10-04)
Vascular endothelial growth factor C (VEGF-C) is a lymphangiogenic factor over-expressed in highly metastatic, cyclooxygenase (COX)-2 expressing breast cancer cells. We tested the hypothesis that tumour-derived VEGF-C may play an autocrine role in metastasis by promoting cellular motility through one
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