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Merck
CN

MAB2120Z

Anti-NCAM Antibody, extracellular, clone ERIC-1, Azide free

clone ERIC-1, Chemicon®, from mouse

别名:

NeuralCellAdhesionMolecule, CD56, MAB2120

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
ERIC-1, monoclonal
Application:
ELISA
immunohistochemistry
western blot
Species reactivity:
human, pig
Citations:
5
Technique(s):
ELISA: suitable
immunohistochemistry: suitable
western blot: suitable
Uniprot accession no.:
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产品名称

Anti-NCAM Antibody, extracellular, clone ERIC-1, Azide free, clone ERIC-1, Chemicon®, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

ERIC-1, monoclonal

species reactivity

human, pig

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgG1

suitability

not suitable for flow cytometry

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... NCAM1(4684)

Analysis Note

Control
Recommended positive control tissue: Neuroblastoma

Application

Anti-NCAM Antibody, extracellular, clone ERIC-1, Azide free is an antibody against NCAM for use in ELISA, WB, IH.
Immunohistology on frozen tissue sections acetone fixation only.

Immunoblotting: Recognizes 120, 140, and 180 kDa NCAM isoforms.

ELISA: 80 ng/mL

Does not work in flow cytometry.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Growth Cones & Axon Guidance

Neurofilament & Neuron Metabolism

Biochem/physiol Actions

Recognizes N-CAM expressed on developing and adult neuroectrodermal tissues in Humans. Neuroectodermal tumors also stain including Elioma, ependymoma, neuroblastoma, medulloblastoma, retinoblastoma and teratoma. Oat cell carcinoma and Wilms tumor are also highly reactive. Will react on Natural Killer cells. Recognizes 120, 140 and 180 kDa NCAM isoforms.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

The previously assigned protein identifier P13592 has been merged into P13591. Full details can be found on the UniProt database.

Immunogen

Epitope: extracellular
Human Retinoblastoma tumor

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: MAB2122

Physical form

Format: Purified
Liquid in PBS. Does not contain any preservatives

Preparation Note

Store at -20°C only. Avoid repeated freeze-thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Ambrose Y Jong et al.
Journal of extracellular vesicles, 6(1), 1294368-1294368 (2017-03-23)
Extracellular vesicles (EVs) have been the focus of great interest, as they appear to be involved in numerous important cellular processes. They deliver bioactive macromolecules such as proteins, lipids, and nucleic acids, allowing intercellular communication in multicellular organisms. EVs are
Boel De Paepe et al.
Biomolecules, 10(4) (2020-04-03)
Myo-inositol exerts many cellular functions, which include osmo-protection, membrane functioning, and secondary messaging. Its Na+/myo-inositol co-transporter SLC5A3 is expressed in muscle tissue and further accumulates in myositis. In this study we focused on the peculiar subgroup of sporadic inclusion body
Stefanie M Hauck et al.
Molecular and cellular biology, 26(7), 2746-2757 (2006-03-16)
Apoptotic cell death of photoreceptors is the final event leading to blindness in the heterogeneous group of inherited retinal degenerations. GDNF (glial cell-line-derived neurotrophic factor) was found to rescue photoreceptor function and survival very effectively in an animal model of
Priyadarsini Kumar et al.
PloS one, 10(8), e0135089-e0135089 (2015-08-13)
Trophoblast differentiation during early placental development is critical for successful pregnancy and aberrant differentiation causes preeclampsia and early pregnancy loss. During the first trimester, cytotrophoblasts are exposed to low oxygen tension (equivalent to~2%-3% O2) and differentiation proceeds along an extravillous

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