MAB2641
Anti-Fibrillin (Pan) Antibody, clone 689
clone 689, from mouse
别名:
EGF-containing fibulin-like extracellular matrix protein 1, Fibrillin-like protein, Extracellular protein S1-5
登录并加购，请在购物车里查看协议价、货期和发货地。
选择规格
变更视图
关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
689, monoclonal
Application:
ELISA, IHC
Citations:
2
biological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
689, monoclonal
species reactivity
mouse
species reactivity (predicted by homology)
chicken (based on 100% sequence homology), human (based on 100% sequence homology)
technique(s)
ELISA: suitable, immunohistochemistry: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... EFEMP1(2202)
General description
~ 350 kDa calculated
Fibrillins are glycosolated and disulfide-rich components of the extracellular matrix belonging to the Fibrillin-LTBP protein family. They serve an important function in both nonelastic and elastic tissues such as eye, bone and blood vessels. The functional units of Fibrillin are known as microfibrils, multiprotein assemblies, which act as structural scaffolding for the limiting of the tissue elasticity, structural integrity of different organ systems, the assembly of elastic fibers, and regulation of BMP growth factor signaling. There are three known isoforms; Fibrillin 1, Fibrillin 2, and Fibrillin 3. Fibrillin 3 is the most recently described member of the Fibrillin family, with highest expression in the brain. Alterations in the microfibril assembly often occur in patients with fibrillinopathies such as; Congenital Contractual Arachnodactyly (CCA) which results in disruption of Fibrillin 2, and Marfan’s syndrome resulting from Fibrillin 1 mutation.
Immunogen
Recombinant protein corresponding to human Fibrillin 3.
Application
Anti-Fibrillin (Pan) Antibody, clone 689 detects level of Fibrillin (Pan) & has been published & validated for use in IH, ELISA.
ELISA Analysis: This antibody has been used by an independent laboratory in ELISA (Corson, 2003).
Biochem/physiol Actions
The antibody recognizes isoforms 1, 2, and 3 of fibrillin.
Physical form
Format: Purified
Analysis Note
Control
Mouse skin tissue
Mouse skin tissue
Evaluated by Immunohistochemistry in fresh frozen mouse skin tissue.
Immunohistochemistry Analysis: 1:200 dilution of the antibody detected Fibrillin (Pan) in fresh frozen mouse skin tissue.
Immunohistochemistry Analysis: 1:200 dilution of the antibody detected Fibrillin (Pan) in fresh frozen mouse skin tissue.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Still not finding the right product?
试用我们的 产品选型工具 工具缩小选择范围
存储类别
12 - Non Combustible Liquids
wgk
WGK 1