生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
67-4H11, monoclonal
种属反应性
rabbit, goat, guinea pig, rat, human, bovine, mouse
制造商/商品名称
Chemicon®
技术
ELISA: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable
同位素/亚型
IgG1κ
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... TIMP2(7077)
免疫原
Synthetic peptide corresponding to amino acids 178-193 of human TIMP-2 (numbered from the propeptide)
YRGAAPPKQEFLDIED
YRGAAPPKQEFLDIED
应用
Anti-TIMP-2 Antibody, clone 67-4H11 detects level of TIMP-2 & has been published & validated for use in ELISA, WB, IH(P).
Immunoblotting
Immunohistochemistry on paraffin-embedded, PLP fixed tissue at 5 μg/mL (see Tomita reference) or frozen tissues at 1 μg/mL (see Ohashi reference).
ElA
Immunohistochemistry on paraffin-embedded, PLP fixed tissue at 5 μg/mL (see Tomita reference) or frozen tissues at 1 μg/mL (see Ohashi reference).
ElA
Research Category
Cell Structure
Cell Structure
Research Sub Category
MMPs & TIMPs
MMPs & TIMPs
生化/生理作用
The antibody specifically reacts with human TIMP-2.
SPECIES REACTIVITY:
Cross-reacts with mouse, rat, guinea pig, rabbit and bovine TIMP-2.
SPECIES REACTIVITY:
Cross-reacts with mouse, rat, guinea pig, rabbit and bovine TIMP-2.
外形
Format: Purified
Liquid in 0.1M Na-Phosphate buffer, pH 7.0 containing 2% protease free bovine serum albumin.
制备说明
Maintain frozen at -20°C in undiluted aliquots for up to 12 months.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: MAB3356
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Manufactured by Daiichi Fine Chemical Co., Ltd
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Wenni Tong et al.
Developmental neurobiology, 70(3), 182-194 (2009-12-18)
A recent study has shown that increased activity of matrix metalloproteinases-2 and metalloproteinases-9 (MMP-2 and MMP-9) has detrimental effect on the brain after neonatal hypoxia. The present study determined the effect of maternal hypoxia on neuronal survivability and the activity
TNF-alpha stimulates activation of pro-MMP2 in human skin through NF-(kappa)B mediated induction of MT1-MMP.
Han, YP; Tuan, TL; Wu, H; Hughes, M; Garner, WL
Journal of Cell Science null
John Ng et al.
Investigative ophthalmology & visual science, 49(12), 5295-5306 (2008-07-22)
Ocular surface squamous neoplasia (OSSN) is an uncommon tumor of the corneal and conjunctival epithelium associated with risk of permanent visual impairment. The purposes of this study were to (1) identify and localize potential mediators in tissue from patients with
Christina Tekle et al.
International journal of cancer, 130(10), 2282-2290 (2011-06-15)
B7-H3, an immunoregulatory protein, is known to play a role in tumor progression. In many cancer types, observed correlations between high B7-H3 expression and poor prognosis have been attributed to involvement in antitumor immunity. However, here we demonstrate a nonimmunological
Tao Xu et al.
Experimental and therapeutic medicine, 10(2), 683-688 (2015-12-02)
The mortality rates associated with colorectal cancer (CRC) are high due to metastasis. Epithelial-to-mesenchymal transition (EMT) is a key step in tumor metastasis. The aim of the present study was to investigate the function of microRNA-20a (miR-20a) in EMT. The
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