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Merck
CN

MAB3494

Sigma-Aldrich

抗ATP合酶抗体,β链,克隆4.3 E8.D1

clone 4.3E8.D1, Chemicon®, from mouse

别名:

Mitochondrial Marker

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关于此项目

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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生物来源

mouse

质量水平

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

4.3E8.D1, monoclonal

种属反应性

mouse, rat, human

制造商/商品名称

Chemicon®

技术

immunocytochemistry: suitable
immunoprecipitation (IP): suitable

同位素/亚型

IgG1

NCBI登记号

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... ATP5B(506)

免疫原

大鼠脑线粒体
表位:β链

应用

免疫细胞化学:使用10xE6细胞或通过间接免疫荧光的粘附样品在室温下以1μ g/mL的浓度放置1小时。建议的固定剂为2-4%多聚甲醛。建议的透化方法是0.5%Triton X-100。

免疫沉淀

最佳工作稀释度必须由最终用户进行确定。
已发表抗ATP合酶抗体,β链,克隆4.3 E8.D1可检测ATP合酶&水平,&经验证可用于IC &IP。
研究子类别
离子通道 & 转运体
研究类别
神经科学

生化/生理作用

识别ATP合酶的β链。ATP合酶的β链是线粒体的有用亚细胞标记。

外形

形式:纯化
纯化的免疫球蛋白。 0.02M磷酸盐缓冲液,0.25M NaCl和0.1%叠氮化钠的液体。

制备说明

自收到之日起,在 2-8° 以未稀释的等分试样可保存 6 个月。

其他说明

浓度:请参考批次特异性浓缩物的分析证书。

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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Glucose metabolism, specifically, hexokinase 2 (HK2), has a critical role in rheumatoid arthritis (RA) fibroblast-like synoviocyte (FLS) phenotype. HK2 localizes not only in the cytosol but also in the mitochondria, where it protects mitochondria against stress. We hypothesize that mitochondria-bound
Daan M Van Den Brink et al.
PLoS genetics, 14(9), e1007627-e1007627 (2018-09-11)
Increasing evidence suggests that dysregulation of lipid metabolism is associated with neurodegeneration in retinal diseases such as age-related macular degeneration and in brain disorders such as Alzheimer's and Parkinson's diseases. Lipid storage organelles (lipid droplets, LDs), accumulate in many cell
Gowtham K Annarapu et al.
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Hemolysis, a pathological component of many diseases, is associated with thrombosis and vascular dysfunction. Hemolytic products, including cell-free hemoglobin and free heme directly activate platelets. However, the effect of hemolysis on platelet degranulation, a central process in not only thrombosis
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BMC developmental biology, 6, 42-42 (2006-09-09)
Human studies suggest, and mouse models clearly demonstrate, that cytomegalovirus (CMV) is dysmorphic to early organ and tissue development. CMV has a particular tropism for embryonic salivary gland and other head mesenchyme. CMV has evolved to co-opt cell signaling networks
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Frontiers in cellular neuroscience, 10, 99-99 (2016-05-06)
High mobility group box 1 (HMGB1) acts a signaling molecule regulating a wide range of inflammatory responses in extracellular space. HMGB1 also stabilizes nucleosomal structure and facilitates gene transcription. Under pathophysiological conditions, nuclear HMGB1 is immediately transported to the cytoplasm

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